A systemic therapy of metastatic renal cancer. A review
Journal Title: Postępy Nauk Medycznych - Year 2011, Vol 24, Issue 2
Abstract
For many years metastatic renal cancer was considered as a chemotherapy-refractory disease. The only two modestly active agents were interleukin 2 and interferon alpha but very few patients benefited from immunotherapy. In recent years, the advances in molecular biology of renal cancer and development of targeted agents have expanded the therapeutic armamentarium. The approved drugs include bevacizumab, sunitinib, sorafenib, temsirolimus, everolimus, and pazopanib. However, relatively many options of possible treatment may sometimes confuse a physician. This paper is a review of the most important clinical trials with the new drugs and an attempt to define the most evidence-based treatment approaches.
Authors and Affiliations
Piotr Potemski
Keywords
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