A THREE YEAR STUDY OF SKIN CANCER IN A CASE WITH XERODERMA PIGMENTOSUM
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 17
Abstract
Xeroderma pigmentosa was first described by Hebra and Kaposis. [1] It’s a rare disorder transmitted by autosomal recessive manner. [2,3] Xeroderma characterized by dry, pigmented skin lesions resultant of severe sensitivity to UV radiation from sun exposure. [4,5,6] Main defect is inability to repair the DNA damage. [5] The prevalence is at 1: 1,000,000, the effects on skin is cumulative and irreversible. [1] There is 1000 fold increase in development of skin cancers, precancerous lesions of mouth and eye. [7,8] We are here presenting a case of xeroderma pigmentosa with skin cancer and its management and follow up.
Authors and Affiliations
Manavalla Subrahmanyam, Jakkula Kishore, Mahalaxmi R
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