A Unique Case: Solitary Fibrous Tumor of the Mandible
Journal Title: International Journal of Oral and Craniofacial Science - Year 2017, Vol 3, Issue 1
Abstract
Solitary fibrous tumors (SFTs) were firstly reported in the pleura by Klemperer and Rabin [1], in 1931. These tumors are rare lesions and most commonly arise in the thoracic cavity [2]. Most of them occur as slow-growing painless masses. Rarely, larger tumors may be a source of paraneoplastic syndromes such as hypoglycemia owing to the production of insulin-like growth factor [3,4]. SFT is a mesenchymal neoplasm, previously nomenclatured as localized benign mesothelioma, submesothelioma, or localized fibrous tumor of the pleura [5]. It is now recognized that this may also occurs in extrapleural sites. Recently, however, SFT has been shown to originate from ubiquitous interstitial stem cells in various human tissues and its histopathological criteria have been established by the aid of immunohistochemistry [6].
Authors and Affiliations
Zanakis Stylianos N, FV Megas
Keywords
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- DOI 10.17352/2455-4634.000023
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