A Useful Predictor for the Prognosis of Acute Pancreatitis: Lactate
Journal Title: Journal of Eurasian Medical Science - Year 2023, Vol 4, Issue 1
Abstract
Objective: In this study, it was aimed to show the prognostic value of Ranson score + lactate level created by adding lactate to Ranson score in patients diagnosed with acute pancreatitis in the emergency department. Material and Methods: One hundred and sixty-three patients with acute pancreatitis were enrolled in this retrospective study. Demographic data, presentation time vital signs, biliary/non-biliary ethiology, Ranson score, hospitalisation clinic, length of hospitalisation, and 30-day mortlity rate data were noted. Ranson score and Ranson score + serum lactate levels were compared according to severity, prognosis and outcome. Results: Complication occurrence ratio was 8.6%. Totally, 160 (98.2%) patients were discharged and 3 (1.8%) patients died. Serum lactate level was significantly related with hospitalization of more than 10 days (p< 0.05). Correct prediction ratio of serum lactate level for complication occurrence during hospitalization was insufficient (p> 0.05). Ranson score and serum lactate levels were significantly correlated (p< 0.05). When we added lactate to Ranson score, correct outcome prediction ratio was significantly higher (p< 0.05). Serum lactate level and length of hospitalization and mortality were positively correlated (p< 0.05). According to ROC analyses, the cut-off level of serum lactate was 17.5 mg/dL for mortality prediction with 100% sensitivity and 75% specificity. Conclusion: Serum lactate level is an important parameter in predicting severity, prognosis and outcome of patients with acute pancreatitis. When serum lactate level is added to RS, better prediction ratios for prognosis and outcome are determined. Serum lactate level can be a useful parameter for emergency clinicians to plan the treatment strategy of acute pancreatitis patients in emergency medicine.
Authors and Affiliations
Mustafa POLAT, Sezai SARI, Mustafa ÇALIŞ, Kemal ŞENER, Adem KAYA, Akkan AVCI, Sadiye YOLCU
Keywords
Related Articles
- EP ID EP715233
- DOI 10.5578/jeurmeds.20239902
- Views 58
- Downloads 0
The Relationship Between Blood Lactate Level and Mortality in Patients Diagnosed with Acute Aortic Dissection in the Emergency Department
Objective: Acute aortic dissection is a time-sensitive and difficult-to-diagnose cardiovascular emergency. The aim of this study was to investigate the relation between blood lactate level and mortality in patients diagn...
Endovascular Treatment of Internal Carotid Artery Aneurysms
Objective: Internal carotid artery (ICA) aneurysms constitute an important subset of cerebral aneurysms. Endovascular treatment interventions are progressively increasing with the advancements in technology. In many deve...
Can the Placement of the Left Ventricular Lead Regarding its Distance From the Ostium of the Middle Cardiac Vein Increase the Rate of Responder Patients to Cardiac Resynchronization Therapy?
Objective: Despite appropriate patient selection criteria and procedural information and technological advances, a high number of patients with cardiac resynchronization therapy (CRT) still remains nonresponsive to treat...
Charlson Comorbidity Index and Mortality in Geriatric Forensic Cases in the Emergency Department
ABSTRACT Objective:Morbidity and mortality are high in trauma patients over 65 years of age. The Charlson Comorbidity Index (CCI) is an assessment tool that has been shown to predict mortality in different clinical popu...
Use of Flow-Diverting Stents in Posterior Circulation Aneurysms
Objective: Flow-diverting stents are safely used for treating carotid artery aneurysms. Its use is limited in areas with dense branching, and more limited in posterior circulation arteries that have dense deep feeders. T...