AB-FUBINACA, A SYNTHETIC CANNABINOID IN “FUNKY GREEN STUFFâ„¢â€
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 11
Abstract
Objective: The objective of this research was to isolate and identify any potential synthetic cannabinoids disguised in the commercially available claimed-to-be herbal scent, known as “Funky Green Stuffâ„¢â€.Methods: Potential synthetic cannabinoids were extracted via percolating the content of the commercial herbal scent bag “Funky Green StuffTM†in methanol. Column chromatographic isolation afforded one main pure compound. Different spectral analyses established the identity of the isolated compound.Results: Chromatographic purification afforded 372 mg (5.2% w/w enrichment ratio) of pure needle crystals. Spectral analyses revealed the identity of the isolated compound as the synthetic cannabinoid AB-FUBINACA, confirming the assumption that a synthetic cannabinoid was disguised as an herbal scent product.Conclusion: Several scent herbal products, also known as “spiceâ€, are used to disguise synthetic cannabinoids. Their detection proved to be troublesome since authentic standards are not yet available. The synthetic cannabinoid, AB-FUBINACA, was isolated from one of these products, and its identity was established based on its spectral data.Â
Authors and Affiliations
Ahmed Rami Ayoun Alsoud, Naser Al-tannak, Haidar Bojabarah, Khaled Y. Orabi
EVALUATION OF ANTICONVULSANT ACTIVITY OF MIMOSA PUDICA ROOT LINN IN SWISS ALBINO MICE
Objective: To evaluate the anticonvulsant activity of ethanolic extract of Mimosa pudica root (EMPR) in experimental mice models.Methods: Ethanolic extract of root parts of Mimosa pudica (EMPR) was prepared by a continuo...
IN SILICO INVESTIGATION OF PHYTOCONSTITUENTS FROM VARIOUS PLANTS AGAINST NEUROINFLAMMATORY MARKERS AS POTENT THERAPEUTIC TARGETS
Abstract Objective: Neuroinflammation is inflammation of the brain and brain tissue. Activation of glial cells (Microgila and astrocytes) takes place during neuroinflammation, due to which a number of inflammatory media...
EX VIVO ANTICOAGULANT ACTIVITY OF 1, 3, 4-OXADIAZOLE DERIVATIVES
Objective: The present medication for the management of arterial thromboembolism (ATE) disorders by anticoagulant therapy highlights its lacunae due to recurrent ATE episodes and indicates the need for better anticoagula...
FORMULATION OF LEVOFLOXACIN AS ORODISPERSIBLE TABLETS USING A READY-MADE BLEND OF EXCIPIENTS COMPARED WITH CLASSIC FORMULATION STRATEGIES
Objective: Orodispersible tablets are designed to undergo rapid dispersal when they are placed in the mouth prior to being swallowed. The aim of this study was to compare the performance of a ready-made excipients blend...
COMPARATIVE STUDY ON THE BENEFICIAL EFFECTS OF TELMISARTAN AND OTHER ANTIHYPERTENSIVE AGENTS IN STROKE PATIENTS
Objective: To compare the beneficial effects of telmisartan with other anti-hypertensive agents during stroke with respect to improvement from neurological dysfunction.Methods: A prospective observational study was perfo...