ABDOMINAL ULTRASONOGRAPHY FINDINGS CORRELATED WITH CD4 COUNTS IN ADULT HIV INFECTED PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 12
Abstract
BACKGROUND The frequency of abdominal disorders in HIV/ AIDS patients is second only to pulmonary diseases. The degree of immunodeficiency is related to the level of CD4+ counts, which is a good index for monitoring the disease progression. It is expected that as the immune status decreases, susceptibility to infection and consequently abnormal sonographic findings should increase. The aim of the study was to perform abdominal ultrasonography in adult HIV-infected patients and correlate these findings with CD4 counts of these patients. MATERIALS AND METHODS 100 adult HIV infected patients were scanned with abdominal ultrasonography and the findings were documented and correlated with their CD4+ counts. Statistical Analysis Used- Data analysis was done using SPSS 21.0. Two-tailed āpā values < 0.05 were considered significant. Settings and Design- This was a prospective cross-sectional study using sample size of 100 HIV infected patients, conducted at the Department of Radiodiagnosis and Imaging, Gandhi Medical College and Hamidia Hospital, Bhopal from March 2015 to September 2016. RESULTS Splenomegaly, splenic granuloma, focal hypoechoic liver lesions, renomegaly, lymphadenopathy and ascites showed significant correlation with CD4 counts. Incidence of increased renal echogenicity, bowel thickening and hepatomegaly was higher in low CD4 classes, but no statistically significant correlation was found. CONCLUSION Abdominal ultrasonography is an excellent and sensitive modality for routine screening of HIV infected patients and focussed assessment in lower CD4 classes and help in early
Authors and Affiliations
Ashish Kaushik, Lovely Kaushal, Divya Pandey, Sudeept Dwivedi
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