About the role of Ureaplasma and Mycoplasma infection in the development of bronchopulmonary dysplasia in infants
Journal Title: Здоров`я дитини - Year 2017, Vol 12, Issue 4
Abstract
The article describes literature data and own observation of ureacoplasmic infection as the cause of the development of bronchopulmonary dysplasia (BPD) in infants. Bronchopulmonary dysplasia as a pathology that occurs in newborn children after resuscitation, in particular oxygen therapy or mechanical ventilation is actively studied by pathomorphologists and clinicians. The questions about the role of infections in the development of BPD in both premature and term infants remain relevant and underinvestigated today. Numerous studies have shown that colonization of the respiratory tract of newborn organisms such as Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma hominis, Cytomegalovirus, is associated with a high risk of developing BPD compared with uninfected children. Ureaplasma urealyticum are the most common microbes found in the infected amniotic fluid, placenta and respiratory tract of newborns, and their ability to cause inflammation in these areas is undeniable. Bronchopulmonary dysplasia associated with these microorganisms is not necessarily directly connected with bacteria, and most likely develops due to their potential to stimulate proinflammatory cytokines (TNF, IL-1 and IL-8) or possible blocking of cytokines (IL-6 and IL-10). The described case illustrates the role of these microorganisms in the development of severe pneumonia outcome in BPD in a term child. A feature of the case is that with proper medical tactics in relation to infected pregnant and as soon as possible early prevention of the development of infection of the newborn, the development of severe, irreversible changes in his lungs could have been avoided.
Authors and Affiliations
S. I. Ilchenko, A. A. Fialkovskaya, S. G. Ivanus
Keywords
Related Articles
- EP ID EP213463
- DOI 10.22141/2224-0551.12.4.2017.107635
- Views 70
- Downloads 0
Modern Approaches to the Diagnosis of Rotavirus Infection in Children
The article presents the results of examining 86 children with a diagnosis of rotavirus infection. We studied and analyzed the structure of rotavirus. It is found that 62.5 % of surveyed children rotavirus infection occu...
Optimization of the laboratory diagnosis of allergies with regard to regional peculiarities
Allergic pathology is one of the most pressing issues in contemporary medicine. The most important task during the treatment of allergic diseases is the determination of cause-significant allergens. Nowadays, the identif...
The Count of Vitamins and Trace Elements in Adolescents with Diffuse Nontoxic Goiter in View of Food Consumption
In adolescents with diffuse nontoxic goiter (DNG), who live in the condition of mild iodine deficiency, in a questionnaire study there was analyzed the diet and its influence on the level of vitamins and minerals. It was...
Types of Diastolic Dysfunction of the Left Ventricle in Adolescents with Myocardial Pathology
In adolescents with myocardial pathology during isometric tests we detected three types of diastolic dysfunction of the left ventricle (LV) of the heart, depending on E/A ratio. The most pronounced signs of diastolic fil...
Basic Aspects of Studying Risk Factors for Respiratory Diseases in Infants and Preschool Children
The represented review of literature enabled to identify the main factors influencing the development of diseases in infants and preschool children. Knowledge of the various risk factors that contribute to the developme...