Abstracts of the 20th Biennal Meeting of the ISN Satellite Symposium "MolecularBasis for Signal Transduction in Neurodegeneration and Neuroregeneration".
Journal Title: Pharmacological Reports - Year 2005, Vol 57, Issue 3
Abstract
Authors and Affiliations
Role of vinpocetine in cerebrovascular diseases.
A cerebrovascular accident, or stroke, is defined as the abrupt onset of a neurological deficit, which can be due to ischemia. Cerebral ischemia is caused by a reduction in blood flow that thereby decreases cerebral meta...
Antidepressant activity of zinc and magnesium in view of the current hypotheses of antidepressant action.
The clinical efficacy of current antidepressant therapies is unsatisfactory; antidepressants induce a variety of unwanted effects, and, moreover, their therapeutic mechanism is not clearly understood. Thus, a search for...
Heme oxygenase/carbon monoxide-biliverdin pathway may be involved in the antinociceptive activity of etoricoxib, a selective COX-2 inhibitor.
The aim of this study was to assess the interaction between the heme oxygenase-1/ biliverdin/carbon monoxide (HO-1/BVD/CO) and cyclooxygenase-2 (COX-2) pathways in the writhing test. Mice were pretreated with 0.1, 1 or 1...
Influence of ABCB1, CYP3A4*18B and CYP3A5*3 polymorphisms on cyclosporine A pharmacokinetics in bone marrow transplant recipients.
The aim of this study was to retrospectively evaluate the effect of polymorphisms in the CYP3A4, CYP3A5 and ABCB1 genes on the dose-adjusted concentration and dose requirement of cyclosporine A(CsA) in Chinese recipients...
Effects of midazolam and buspirone on in vivo concentration of amino acids and monoamine metabolites in the rat hippocampus.
The effects of anxiolytic doses of buspirone and midazolam (established in the conditioned fear test) on extracellular concentrations of glutamate, GABA, serotonin and dopamine metabolites in the hippocampus were examine...