Acantholytic squamous cell carcinoma: Pathological study of three cases in Ecuador

Journal Title: Journal of Surgical Dermatology - Year 2017, Vol 2, Issue 5

Abstract

Adenoid squamous cell carcinoma is an uncommon histopathological variant of squamous cell carcinoma characterized by acantholysis of tumor cells creating pseudolumina and the appearance of glandular differentiation. It is also known as pseudoglandular, pseudoangiosarcomatous, adenoid, epithelioma dyskeratoticum, or adenoacanthoma. In this article, we describe and analyze three cases of acantholytic cell carcinoma. The purpose is to verify if the data of our cases can be validated with scientific information. All our cases presented lesions in the face, and in one of them the developed tumor on the skin showed actinic keratosis. The other two tumors were located in the right side of the face, and both were big: the bigger tumor was approximately 8 × 4 cm and the other one with a size of 6 × 2.5 cm. Due to the size and location, they were both send to the oncologist for treatment. One of our cases showed metatypical carcinomas accompanied by acantholytic variant of squamous cell carcinoma. None of our cases presented metastasis. The histopathological finding were keratinized squamous tumor cell type, adenoid structures with round spaces with a defined wall of at least one-cell width, and spaces with isolated or group of dyskeratotic cells.

Authors and Affiliations

Eduardo Garzón Aldas, Gabriela Torres

Keywords

Related Articles

Hyaluronidase in the treatment of papular dermal mucinosis: First case reported in North America

Papular mucinosis is an uncommon, idiopathic disorder characterized by dermal mucin deposition and increased collagen in the skin and internal organs. Its clinical presentation is characterized by dome-shaped, flesh colo...

Facial laser surgery

Lasers have a number of clinical applications on the face, ranging from aesthetic uses such as the rejuvenation of ageing face to functional ones such as the correction of bleeding vascular malformations. The vast growin...

Alopecia neoplastica: An uncommon presentation of metastatic breast carcinoma

Cutaneous metastasis may correspond to the initial clinical presentation of hidden internal malignancies. In patients presenting said neoplasia, clinical manifestations of breast cancer reaches 23.9%. Considering that ne...

Giant cell tumor of tendon sheath—Use of fine-needle aspiration cytology for diagnosis

Giant cell tumour of the tendon sheath (GCTTS) is a slow-growing, usually painless benign lesion of soft tissues. We report the case of a 38-year-old male with a painless, slowly enlarging swelling on right thumb in orde...

Trichofolliculoma of the nasal vestibule

The presence of a nasal vestibule mass can be challenging in obtaining diagnosis and treatment due to the features of nasal vestibule. There are various types of diseases that can involve the nasal vestibule. Here, we pr...

Download PDF file
  • EP ID EP680027
  • DOI -
  • Views 187
  • Downloads 0

How To Cite

Eduardo Garzón Aldas, Gabriela Torres (2017). Acantholytic squamous cell carcinoma: Pathological study of three cases in Ecuador. Journal of Surgical Dermatology, 2(5), -. https://europub.co.uk/articles/-A-680027