Accuracy and Predictability of PANC-3 Scoring System over APACHE II in Acute Pancreatitis: A Prospective Study

Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 2

Abstract

Introduction: Acute Pancreatitis (AP) is one of the common conditions encountered in the emergency room. The course of the disease ranges from mild form to severe acute form. Most of these episodes are mild and spontaneously subsiding within 3 to 5 days. In contrast, Severe Acute Pancreatitis (SAP) occurring in around 15-20% of all cases, mortality can range between 10 to 85% across various centres and countries. In such a situation we need an indicator which can predict the outcome of an attack, as severe or mild, as early as possible and such an indicator should be sensitive and specific enough to trust upon. PANC-3 scoring is such a scoring system in predicting the outcome of an attack of AP. Aim: To assess the accuracy and predictability of PANC-3 scoring system over APACHE II in predicting severity in an attack of AP. Materials and Methods: This prospective study was conducted on 82 patients admitted with the diagnosis of pancreatitis. Investigations to evaluate PANC-3 and APACHE II were done on all the patients and the PANC-3 and APACHE II score was calculated. Results: PANC-3 score has a sensitivity of 82.6% and specificity of 77.9%, the test had a Positive Predictive Value (PPV) of 0.59 and Negative Predictive Value (NPV) of 0.92. Sensitivity of APACHE II in predicting SAP was 91.3% and specificity was 96.6% with PPV of 0.91, NPV was 0.96. Conclusion: Our study shows that PANC-3 can be used to predict the severity of pancreatitis as efficiently as APACHE II. The interpretation of PANC-3 does not need expertise and can be applied at the time of admission which is an advantage when compared to classical scoring systems.

Authors and Affiliations

Surag Kajoor Rathnakar, Vikram Hubbanageri Vishnu, Shridhar Muniyappa, Arun Prasath

Keywords

Related Articles

Aspects of the Sinonasal Sarcoidosis Manifestations in Iran

ABSTRACT Introduction: Sinonasal Sarcoidosis (SNS) is the most common involvement of upper respiratory tract sarcoidosis disease. Not much data is available on the detailed diagnostic aspects of Iranian sinonasal sarcoi...

Extramedullary Plasmacytoma Presenting as Lung Cancer

ABSTRACT Extramedullary Plasmacytoma (EMP) is a rare plasma cell tumour without any other systemic characteristics of multiple myeloma. They are commonly observed in tissues of the upper aerodigestive tract and are extre...

The Ameliorating Effect of Beta Vulgaris Extract on Memory and Learning Impairment Induced by Lesions of the Nucleus Basalis of Meynert in Rat

Introduction: Alzheimer's Disease (AD) affects a large number of aged populations. The current therapeutic approach to treat cognitive loss associated with AD is cholinergic enhancement strategy using muscarinic or nicot...

Vertebral Cryptococcosis Infection in an Immunocompetent Host: A Rare Case Report

ABSTRACT Cryptococcosis is a systemic mycosis caused by yeast like fungus Cryptococcus neoformans. The infection results from inhalation of fungal spores in soil, house dust and in pigeon and other bird excreta. Infectio...

Download PDF file
  • EP ID EP332831
  • DOI 10.7860/JCDR/2017/23168.9375
  • Views 117
  • Downloads 0

How To Cite

Surag Kajoor Rathnakar, Vikram Hubbanageri Vishnu, Shridhar Muniyappa, Arun Prasath (2017). Accuracy and Predictability of PANC-3 Scoring System over APACHE II in Acute Pancreatitis: A Prospective Study. Journal of Clinical and Diagnostic Research, 11(2), 10-13. https://europub.co.uk/articles/-A-332831