ACUTE AND SUB-ACUTE TOXICITY STUDY OF COMPOUND SIDDHA DRUG LAGU SEENA CHOORANAM FOR THE MANAGEMENT OF SCABIES
Journal Title: International Journal of Pharmacognosy - Year 2015, Vol 2, Issue 10
Abstract
Herbals are playing a major role in Siddha system of medicine. Herbals contain plant materials as their pharmacologically active components. The aim of the study is to evaluate the acute and sub-acute toxicity of the Siddha herbal preparation Lagu Seena Chooranam (LSC) for the treatment of Scabies in the pediatric age group. For acute studies, different doses of LSC were administered orally to rats once daily for one week. For sub-acute studies, different doses were administered orally to rats once daily for 28 days in various doses at 200, 400 mg/kg of body weight. Detailed hematological, biochemical, necropsy and histopathological evaluation of organs were performed for all animals. Histopathological analysis revealed that spleen, testes, pancreas, lung, liver, brain, heart, stomach, intestine, bone, ovary, and kidney tissues of treated groups did not show any signs of toxicity. No destruction in hepatic, renal, hemopoietic functions was observed throughout the study.
Authors and Affiliations
A. Silambarasan et al.
Keywords
Related Articles
- EP ID EP556798
- DOI -
- Views 117
- Downloads 0
COMPARATIVE STUDY OF ANTIMICROBIAL EFFECT OF NIGELLA SATIVA SEED EXTRACTS FROM DIFFERENT GEOGRAPHIES
Prophet Mohammed calls Nigella sativa seed as a medicine of blessings. Nigella sativa isan herbaceous plant and cultivated in Middle East, South East Asia and some part of the Europe. Nigella sativa seed has been in use...
ANTIMICROBIAL AND ANTIOXIDANT POTENCY OF DENDROPTHOE FALCATA LINN.
The World Health Organization survey indicated that about 70-80% of the world’s populations rely on non-conventional medicine, mainly of herbal sources, in their primary healthcare. Among them parasitic plants are well k...
EVALUATION OF LAXATIVE ACTIVITY OF VARIOUS FRUIT EXTRACTS OF ANETHUM GRAVEOLENS L.
Anethum graveolens an important medicinal plant and one of the most widely cultivated species of the family (Umbelliferae). It is highly valued from time immemorial because of its vast medicinal properties. The present w...
PHYTOCHEMISTRY AND PHARMACOLOGICAL ACTIVITIES OF MORINGA OLEIFERA
Moringa oleifera can grow well in the humid tropics or hot, dry lands, can survive destitute soils, and is little affected by drought. It tolerates a wide range of rainfall with minimum annual rainfall requirements estim...
MORTALITY AND REPELLENT ACTIVITY OF CLERODENDRUM VISCOSUM VENT. (VERBENACEAE) AGAINST SITOPHILUS ORYZAE (COLEOPTERA: CURCULIONIDAE)
In continuation of our study we have screened out the root, leaf, and stem of C. viscosum against rice weevil, S. oryzae extracted into ethanol, ethyl acetate, and chloroform. A correlation was found between the insectic...