Acute and subacute toxicity of the aqueous extract of Amaranthus viridis (Amaranthaceae) leaves in rats
Journal Title: UNKNOWN - Year 2018, Vol 7, Issue 4
Abstract
Amaranthus viridis is a plant of the family Amaranthaceae, used by traditional medicine in the treatment of several diseases. The aim of this study was to evaluate the toxicological activities of A. viridis. To assess these activities, two types of test were performed: Acute and subacute toxicity test. Phytochemical analysis performed on the aqueous extract of A. viridis revealed the presence of polyphenol, flavonoids, tannins, sterol-polyterpenes, Saponosids, cardiac glycosides, traces of alkaloids and leucoanthocyanines. The aqueous extract of Amaranthus viridis showed no evidence of single dose toxicity (2000 mg/kg) when studying acute toxicity. The subacute toxicity study of the aqueous extract of A. viridis at doses of 200, 400 and 600 mg/kg showed no signs of toxicity on biochemical, hematological or histological parameters. The results showed that A. viridis does not cause toxicity at the doses studied.
Authors and Affiliations
Affy Mataphouet Emmanuel, Kouakou Koffi Roger, Douhoure Gnaore Toussaint, Kouakou Koffi
Keywords
Related Articles
- EP ID EP589791
- DOI -
- Views 67
- Downloads 0
In vivo antidiabetic activity of aqueous and ethyl acetate leaf extract of Senna singuena (Delile) in alloxan induced diabetic mice
The folkloric claims that Senna singuena confers antidiabetic effect to prescribed patients has received long term clinical application accompanied by limited scientific data in support of such claims. This study aimed a...
Pharmacognostical and Pharmaceutical Evaluation of Poly Herbal Formulation: Agastyaharitaki Avaleha
In the era of increasing demand for indigenous medicines, maintaining quality standards is the need of the hour. Agastyaharitaki Avaleha is a poly herbal formulation used for the management of various diseases like kasa,...
Response of brinjal (Solanum melongena L.) varieties for resistance against root-knot nematode, Meloidogyne incognita race-1
Thirty brinjal varieties were screened for their resistance / susceptibility to root-knot nematode (Meloidogyne incognita race-1) infestation. Out of 30 brinjal varieties, eighteen varieties viz., Black Beauty, Brinjal 1...
Phytochemical screening and antimicrobial activities of the stem bark of Allanblackia parviflora Chev. (Clusiaceae)
This study has successfully explored the photochemistry and antimicrobial properties of the methanolic, aqueous and pet ether stem bark extracts of Allanblackia parviflora (Chevalier) (Clusiaceae). The qualitative phytoc...
Kidney disorders and management through herbs: A Review
Kidneys have a vital role in the normal physiology of humans. Worldwide chronic kidney disease has become a major cause for disability and in worst circumstances leads to death. Major renal disorders occur due to diabete...