Acute Coronary Syndrome (ACS) in the Young: Angiographic Features and Risk Factor Analysis of Patients with ACS before the Age of 35 Years
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 4
Abstract
Introduction: Although there are many studies of acute coronary syndrome (ACS) in young, there are very few studies of ACS in age group <35 years. Besides, there is hardly any data available about clinical and angiographic profile of our regional population in our young ACS patients <35 years of age. Aims and Objectives: The aim of the study is to study the clinical and angiographic profile in age group <35 years presenting as ACS. Material and Methods: It was a prospective hospital-based study. All patients with age <35 years presenting as acute myocardial infarction (MI) from March 2012 to March 2014 were enrolled. Clinical presentation, coventional risk factors, and angiographic profiles were noted. Results: A total of 30 patients were studied. The mean age of the patients was 30.87 ± 3.72 (range 21-35) years. All patients were males. Of these 14 patients had anterior wall ST elevation MI and other two had anterior wall non-ST elevation MI. 14 patients had infarct of the inferior wall. Smoking (66.66%) and dyslipidemia (50%) were two major conventional coronary risk factors followed by family history of premature coronary artery disease (26.6%) and hypertension (13.3%). The most common arteriographic finding was the involvement of one vessel (60%) followed by zero-vessel disease (23.33%), double-vessel disease was seen in only three patients and there were two patients with triple-vessel disease. None of the patients had left main involvement. The most common vessel to be involved was left anterior descending (LAD) (83.3%). Conclusion: Smoking and dyslipidemia are the most common modifiable conventional risk factors. Single-vessel disease of LAD was common anatomic presentation. Further larger studies are needed to confirm the findings and implement various preventive strategies to decrease disease burden.
Authors and Affiliations
Mohmad Iqbal Wani, Aamir Rashid, Jahangir Rashid Beig, Shahood Ajaz
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