Acute Hepatic Insufficiency Disclosing Congenital Syphilis in a Neonate

Journal Title: Journal of Advances in Medicine and Medical Research - Year 2016, Vol 12, Issue 11

Abstract

Congenital syphilis is a maternal-fetal infection caused by Treponema pallidum. Early signs are characteristic skin lesions, lymphadenopathy, hepatosplenomegaly, failure to thrive, blood-stained nasal discharge, perioral fissures, meningitis, choroiditis, hydrocephalus, seizures, intellectual disability, osteochondritis, and pseudoparalysis (Parrot atrophy of newborn). We report the case of a new born on day 1 of life hospitalized for respiratory distress. Clinical examination showed signs of respiratory retraction with hypotonia. The assessment carried out revealed: severe liver insufficiency and infected cerebrospinal fluid (CSF) with sterile culture. The diagnosis of congenital syphilis in our patient was confirmed by a positive serology in the neonate and her mother. The outcome was fatal.

Authors and Affiliations

M. A. Radouani, Y. Taboz, H. Benkirane, M. Mrabet, A. Barkat

Keywords

Related Articles

Hepatotoxicity and Nephrotoxicity of Automobile Gas Oil (Diesel Oil) and Its Biochemical Effect on Hematological and Oxidative Stress Parameters in Wistar Male Albino Rats

Aims: The study was designed to investigate the hepatotoxicity and nephrotoxicity of automobile gas oil (Diesel oil) and its biochemical effect on hematological and oxidative stress parameters in Wistar male albino rats....

Outcomes of Acute Kidney Injury Patients with and Without Cancer: A Single Center Study

Background: Acute kidney injury (AKI) is a frequent complication in hospitalized patients. Incidence of AKI in hospitalized patients with cancer is increasing, but there have been few studies on AKI in patients with canc...

Role of Diffusion Weighted Magnetic Resonance Imaging at 3-T in Staging of Endometrial Cancer and Correlation to Histopathology

Aim: To investigate the value of diffusion weighted imaging (DWI) at 3-T MR in staging of endometrial cancer and the correlation to histopathology. Study Design: A retrospective study. Place and Duration of Study: CT-M...

An Investigation of the Retinal Layers in an Experimental Model of Multiple Sclerosis; a Histopathological and Immunohistochemical Study

Background: Animal model of multiple sclerosis is a demyelinating and inflammatory disorder of central nervous system and eye. Histological evaluation in eyes in experimental autoimmune encephalomyelitis (EAE) models dem...

The Management of Vesico-vaginal Fistula in State Specialist Hospital Maiduguri, Borno State

Background: Vesico-vaginal fistula is a common problem that has public health significance. Aims: To determine the epidemiology, causes as well as the outcomes of VVF repair in the Department of Obstetrics and Gynaecolog...

Download PDF file
  • EP ID EP340447
  • DOI 10.9734/BJMMR/2016/22286
  • Views 69
  • Downloads 0

How To Cite

M. A. Radouani, Y. Taboz, H. Benkirane, M. Mrabet, A. Barkat (2016). Acute Hepatic Insufficiency Disclosing Congenital Syphilis in a Neonate. Journal of Advances in Medicine and Medical Research, 12(11), 1-4. https://europub.co.uk/articles/-A-340447