Acute Hypertension during Clonidine Taper in an Infant with Neonatal Abstinence Syndrome

Abstract

A 2,600-gram infant treated with methadone and clonidine for Neonatal Abstinence Syndrome (NAS) developed acute hypertension following initiation of the clonidine taper, requiring treatment with a calcium channel blocker. While transient hypertension after discontinuing alpha-2 agonist treatment is common, prolonged elevation of blood pressure is uncommon. Thus, more gradual tapering and careful monitoring of blood pressure following discontinuation of clonidine in newborn patients could be warranted.

Authors and Affiliations

Mark Greenberg, Alyssa Brzenski, Dawn Reeves

Keywords

Related Articles

Sustained-Release Bupropion Overdose: A Case Report

Bupropion is an atypical antidepressant with a unique aminoketone structure similar to amphetamines. A narrow therapeutic margin is evident from observational studies that show seizure activity with doses of 400-600 mg o...

Hepatic Artery Mycotic Aneurysm and Microabscesses: A Rare Complication of Infective Endocarditis with Classical Quincke’s Symptom

Hepatic artery branch mycotic aneurysm causing intrahepatic biliary dilatation and associated with hepatic micro abscesses is a rare complication of infective endocarditis and patient presenting with classical Quincke’s...

Colonoscopy-induced Enteropathogenic Escherichia coli Bacteremia Diagnosed by Serum Polymerase Chain Reaction Method

We report the case of colonoscopy induced enteropathogenic Escherichia coli (EPEC) bacteremia by bacterial translocation. A 58-year old woman who complained of abdominal pain was performed colonoscopy. Intestinal mucosal...

Raltegravir in the Treatment of HIV-¬2 Infection: A Report of Eight Cases

Background: Although endemic in West Africa, HIV-2 infection dissemination is limited to about 1.2 million people worldwide. However, the prevalence of HIV-2 infection is in Portugal disproportionately high, similarly to...

Internal Resorption: A Report of Two Cases

Internal resorption is generally noted in teeth with previous history of trauma. Often the tooth is asymptomatic. The diagnosis of this condition at an early stage improves the prognosis of such teeth. Therefore it is im...

Download PDF file
  • EP ID EP327761
  • DOI 10.9734/IJMPCR/2016/29918
  • Views 90
  • Downloads 0

How To Cite

Mark Greenberg, Alyssa Brzenski, Dawn Reeves (2016). Acute Hypertension during Clonidine Taper in an Infant with Neonatal Abstinence Syndrome. International Journal of Medical and Pharmaceutical Case Reports, 8(1), 1-5. https://europub.co.uk/articles/-A-327761