Acute Liver Failure in children – A constant challenge for the treating intensivist
Journal Title: Journal Of Pediatric Critical Care - Year 2016, Vol 3, Issue 4
Abstract
Pediatric acute liver failure (ALF) is a rare complex clinical syndrome with a fatal outcome, if not diagnosed and treated at the right time. ALF in children can be difficult to recognize and is very different from ALF in adults; in terms of definition, etiology, symptomatology and management. The causes of ALF in children represent a large heterogeneous list, which vary by age and geographical location. The management of ALF mandates multidisciplinary approach with comprehensive intensive and supportive care; which at times is complex and can be challenging to a pediatric intensivist. The key steps in management are to monitor and support affected organ systems; anticipate, identify and treat complications; and maintain optimal clinical condition till spontaneous recovery or liver transplantation. This review describes definitions, etiopathogenesis, clinical features and the most recent management strategies, including emergency liver transplantation considerations in pediatric ALF.
Authors and Affiliations
Maninder Singh Dhaliwal, Veena Raghunathan, Neelam Mohan, Akash Deep
Keywords
Related Articles
- EP ID EP339581
- DOI 10.21304/2016.0304.00144
- Views 79
- Downloads 0
Airway Anomalies In Paediatric Congenital Heart Diseases: Utility Of Bedside Fibreoptic Flexible Bronchoscopy
.
High Frequency Oscilatory Ventilation – Current update
This article intends to review literature on high frequency oscillatory ventilation and describe its main clinical applications for children. There is increasing evidence that strategies aimed at preventing ventilator-in...
Simulathon - Pediatric Trauma simulation training in-situ across India
.
OSCE : Data Interpretation
-
Triple “A” Syndrome Presenting As Recurrent Chronic Sinusitis With Pneumonia, Septic Shock And Meningoencephalitis In A 13 Years Old Boy
Background : Triple A syndrome (All grove syndrome) is a rare autosomal recessive disorder characterized by the clinical triads of adrenal insufficiency, achalasia cardia and alacrima.It was first described by Allgrove i...