Acute Myeloid Leukemia with Bombay Blood Group: A Diagnostic and Therapeutic Challenge
Journal Title: GUJARAT CANCER SOCIETY RESEARCH JOURNAL - Year 2018, Vol 20, Issue 2
Abstract
Bombay blood group is a very rare type of blood group with incidence of 0.0004% in the world. Individuals with rare Bombay phenotype do not express H antigen, the antigen which is present in blood group O. Bombay blood group can be misdiagnosed because usual tests for ABO blood group system would show them as group O and patient can be transfused mismatched blood which can be fatal. Here we report a case of 42 years old female diagnosed as Acute Myeloid Leukemia (AML) at private hospital and transfused 4 units of O positive PCV following which she developed jaundice and was referred to GCRI. Our blood bank had difficulty in finding the exact blood group but on subsequent work up it was found to be Bombay blood group and it was reconfirmed at National Institute of Immunology, Mumbai. As Bombay blood group is rare in Gujarat she was referred to Mumbai for further treatment. None of her siblings tested positive for Bombay blood group
Authors and Affiliations
Priyanka Patel, Asha Anand, Sonia Parikh, Harsha Panchal, Apurva Patel, Sandip Shah, Rima Kusumgar
Presentations at the Clinical Meetings
Presentations at the Clinical Meetings
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