ACUTE TRANSFUSION REACTIONS IN PATIENTS ADMITTED TO HOSPITAL- A CLINICAL STUDY
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 2
Abstract
Background: Any unfavorable event occurring in a patient during or after transfusion of blood and blood components and for which no other reason is known as a transfusion reaction. Transfusion is a frequently administered therapy among the critically ill patients, to treat a condition leading to significant morbidity or mortality that cannot be prevented or managed effectively by other means. The present study was conducted to evaluate acute transfusion reactions occurring in patients admitted to hospital. Materials & Methods: This study was conducted in year 2014. It included 220 patients who had acute transfusion reactions admitted to ICU. A transfusion reaction form with all the blood products, containing patient’s name, age, identification number, name of the ICU, ABO-Rh group of the patient, type of blood product and blood unit registration number was issued. Results: Out of 220 patients, 110 were males and 100 were females. The difference was non – significant (P -1). Out of 10301 numbers of various units transfused, 220 patients developed ATRs. It included 4210 units of packed red cells, 2871 units of fresh frozen plasma and 3220 platelet concentration. The prevalence rate was 2.1%. ATRs were 65 out of 2564 units of transfusion in emergency, 47 out of 2010 units of transfusion in medical ICU, 33 out of 1925 units of transfusion in surgical ICU, 45 out of 2108 units of transfusion in cardiac ICU and 30 out of 1694 units of transfusion in pediatric ICU. Maximum reactions occurred in emergency ICU with 2.5% prevalence rate. Maximum reactions were febrile non hemolytic transfusion reactions (132) occurring due to packed red cell (80), fresh frozen plasma (32) and platelet concentrate (20) followed by allergic reactions (55), non specific reactions (18), transfusion related acute lung injury (TRALI) (6), transfusion related sepsis (5) and hemolytic reactions (4). Conclusion: Blood transfusion is a vital therapeutic procedure and there is need to monitored each transfusion carefully with prompt recognition and treatment of ATRs. A well knowledge about these reactions can only prevent their occurrence.
Authors and Affiliations
Devendra Kumar Katiyar, Rahul Kumar
Keywords
Related Articles
- EP ID EP556003
- DOI -
- Views 125
- Downloads 0
A Clinical Study on Fronto Nasal Flap for Nasal Tip Reconstruction: A Multidisciplinary Approach
Reconstruction of any part of face and oral cavity is always very challenging to any concerned specialty and it should involve a team of specialists from different specialties to overcome the problems faced while doing a...
Blood Pressure Response to Azilsartan in Hypertensive Patients
Background: Azilsartan is a novel angiotensin receptor blocker (ARB) being created for hypertension treatment. The primary point of this article is to assess the viability, wellbeing, and clinical part of azilsartan in h...
Classifying Impacted Mandibular Third Molar & its Relation with Inferior Alveolar Canal- A Clinical Study
Background: The exact knowledge of relation of impacted mandibular third molar with inferior alveolar canal is useful in removing the tooth. The present study was conducted to assess the relationship with impacted mandib...
ANALYSIS OF CASES OF ORGANOPHOSPHOROUS POISONING- A CLINICAL STUDY
Background: Human deaths following poisoning are a matter of great concern. It has high mortality and morbidity. The present study was conducted to assess the organophosphorous poisoning with respect to age, gender, educ...
Diastolic Dysfunction and Mortality in Early Severe Sepsis and Septic Shock - A Prospective Echocardiography Study
Background: Severe sepsis or septic shock is suggested to be a cause of significant cardiovascular dysfunction. Left ventricular diastolic dysfunction is common in septic patients. Aim: To evaluate the incidence of the d...