ADDITIONAL VALUE OF POST-THERAPY 131I SPECT/CT IN PATIENTS WITH DIFFERENTIATED THYROID CANCER

Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 19

Abstract

BACKGROUND Generally, it is seen that SPECT/CT images are more useful than the planar images. We compared post-therapy 131I imaging findings on planar and SPECT/CT scans to assess the clinical utility of SPECT/CT in management of patients with differentiated thyroid cancer. MATERIALS AND METHODS Post-therapy imaging was performed at 4-7 (when 5mR/hrs. exposure rate were observed by the survey meter) days after 131I administration and all patients underwent whole-body scintigraphy and SPECT/CT scanning on the same day. A generalised McNemar1 was used to determine to establish the agreement between planar whole-body imaging and SPECT/CT for the assignment of benign, equivocal and malignant findings. RESULTS In 44 patients, 32 of the 44 patients underwent postsurgical 131I ablation of residual thyroid tissue and 12 of 44 patients, 2 patients were treated twice. Hence, a total of 46 scans were analysed. SPECT/CT helped to localise focal iodine uptake and characterise it as either normal or abnormal thereby reducing the need for additional imaging studies. In post-thyroidectomy patients, SPECT/CT findings affected the ATA risk classification with implications for management by changing the interval for clinical followup and the need for additional imaging and laboratory tests. Our study found an 11% change in nodal status in the postsurgical group. Change in patient management was observed in 18%. CONCLUSION SPECT/CT enabled more accurate characterisation of focal iodine accumulation in patients.

Authors and Affiliations

Satyawati Deswal, Dhananjay Kumar Singh, Vibhor Mahendru, Kavindra Pratap Singh

Keywords

Related Articles

A STUDY ON THE EPIDEMIOLOGY OF ECTOPIC PREGNANCY IN A TERTIARY CARE CENTRE IN NORTH KERALA

Ectopic pregnancy is still the leading cause of maternal death in the first trimester. It is a nightmare for the obstetrician Globally, there is an increased incidence of ectopic pregnancy due to the increase in the inci...

EVALUATION OF CAESAREAN SECTION RATE USING ROBSON’S TEN GROUP CLASSIFICATION IN A TEACHING HOSPITAL

BACKGROUND Nowadays, caesarean section has become rampant in obstetric practice. There has been a dramatic increase in caesarean section rate all over the world over the last two decades and presently exceeds 30% in some...

AN ASSESSMENT OF CAUSE OF VISUAL IMPAIRMENT AMONG STUDENTS OF BLIND SCHOOL IN BASTAR DISTRICT, CHHATTISGARH

BACKGROUND About 1.4 million children in the world are either visually impaired or blind causing hindrance to lead a normal lifestyle. Among various reasons for childhood blindness, the most common preventable cause of b...

CERVICAL CYTOLOGY (THE BETHESDA SYSTEM) AND COLPOSCOPIC GUIDED BIOPSY CORRELATION IN NEOPLASTIC CERVICAL LESIONS

Cervical cancer is a significant health problem worldwide among women. Cancer cervix is the most common cancer in developing countries. It is considered as preventable cancer since there is availability of screening meth...

PRIMARY TRANSANAL ENDORECTAL PULL-THROUGH FOR HIRSCHSPRUNG’S DISEASE IN NEONATES- OUR EARLY EXPERIENCE

BACKGROUND The most common cause of bowel obstruction in the neonates is Hirschsprung’s disease. Traditionally Hirschsprung’s disease was managed in stage procedure of colostomy, the definitive pull-through followed by c...

Download PDF file
  • EP ID EP215056
  • DOI 10.18410/jebmh/2017/208
  • Views 84
  • Downloads 0

How To Cite

Satyawati Deswal, Dhananjay Kumar Singh, Vibhor Mahendru, Kavindra Pratap Singh (2017). ADDITIONAL VALUE OF POST-THERAPY 131I SPECT/CT IN PATIENTS WITH DIFFERENTIATED THYROID CANCER. Journal of Evidence Based Medicine and Healthcare, 4(19), 1062-1066. https://europub.co.uk/articles/-A-215056