Adherence of Adult Hypertensive Patients to Their Medications in Riyadh, Kingdom of Saudi Arabia

Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1

Abstract

Background: The treatment of hypertension depends on pharmacological therapy and non-pharmacological which mean lifestyle modification to decrease blood pressure and prevent the complication. Low-adherent patients have a higher risk of cardiovascular events than high-adherent patients. There is many factors affect antihypertensive patient’s adherence. Objective: To study the adherence states in adult hypertensive patient in Riyadh City as well as to explore the barriers that affect patient adherence. Methods: This is a cross-sectional study carried out throughout the period June-December, 2016 at the outpatient clinic of Chronic Disease Unit, Al-Morslat Primary Health Care Center, Al-Masef Primary Health Care Center and Al-Iman General Hospital, in Riyadh Region, Saudi Arabia. It included hypertensive patient’s prescribed antihypertensive medication at least one year. Qualitative questionnaire was designed to collect data regarding socio-demographic characteristics, medical and therapeutic characteristics and adherence to antihypertensive medications. Results: The study included 375 hypertensive patients. The age of more than half of them (55.8%) exceeded 50 years. Almost half of them were females (50.9%). Only17.3% of the participated hypertensive patients had health insurance. The duration of hypertension exceeded 6 years among more than half of them (54.4%). Co-morbid diseases were reported among 56.9% of the patients. Overall, good adherence to anti-hypertension drugs was reported by 20% of patients. Multivariate logistic regression analysis revealed that smoker hypertensive patients were at almost 4-fold increase risk to not adhere to antihypertensive patients compared to non-smokers (Adjusted OR: 4.27 95% CI: 1.69 - 10.76, p=0.002). Patients with co-morbid diseases were more significantly like to not adhere to antihypertensive drugs opposed to those without co-morbid chronic diseases (Adjusted OR: 3.20 95% CI: 1.73-5.96, p<0.001). Patients who had 4-5 various dugs/day were 32% less likely to be not adherent to anti-hypertensive drugs compared to those who had 1-3 drugs/day (Adjusted OR: 0.68 95% CI: 0.23-0.91, p=0.001). Considering patients who had one daily dose of antihypertensive as a reference category, those on twice daily per day were at lower risk of being not adherent to antihypertensive (Adjusted OR: 0.42 95% CI: 0.22-0.81, p=0.010). Conclusion: Good adherence to anti-hypertensive medications in Riyadh is suboptimal as only one fifth of patients were highly adherent to anti-hypertensive medications. Our study highlights some factors that may influence adherence levels including smoking status, presence of co-morbid diseases, number of medications taken daily and number of daily anti-hypertensive doses.

Authors and Affiliations

Hadeel Ibrahim Al-Zahrani, Yousif Asiri, Yazeed M Aljarboua, Abdulrhman Saad Abudalli, Amal. H Al-Najjar

Keywords

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  • EP ID EP529685
  • DOI 10.21276/ijmrp.2018.4.1.040
  • Views 68
  • Downloads 0

How To Cite

Hadeel Ibrahim Al-Zahrani, Yousif Asiri, Yazeed M Aljarboua, Abdulrhman Saad Abudalli, Amal. H Al-Najjar (2018). Adherence of Adult Hypertensive Patients to Their Medications in Riyadh, Kingdom of Saudi Arabia. International Journal of Medical Research Professionals, 4(1), 202-209. https://europub.co.uk/articles/-A-529685