Adhesion molecules; novel tools in the cancer jigsaw <br />
Journal Title: Αρχεία Ελληνικής Ιατρικής - Year 2008, Vol 25, Issue 2
Abstract
In the present study the topic of adhesion molecules regarding their involvement in the whole carcinogenetic process is discussed in detail. Until now, more than a hundred adhesion molecules have been fully identified, and their role so in normal as in various pathologies, including cancer, is under continuous investigation. Adhesion molecules are involved so in the initial invasive carcinogenetic process, as in the metastatic foci creation. The role of some members of integrins, cadherins, immunoglobulin gene superfamily, selectins and CD44 that comprise adhesion molecules is discussed. Their role in diagnosis, prognosis, and possibly in treatment, is also referred.
Authors and Affiliations
K. CHARALABOPOULODS
Keywords
Related Articles
- EP ID EP139340
- DOI -
- Views 87
- Downloads 0
The effect of N-acetylcysteine on the serum levels of asymmetric dimethylarginine and nitrogen oxide in patients on hemodialysis
OBJECTIVE To investigate the effect of oral administration of the antioxidant drug N-acetylcysteine (NAC) on the serum levels of asymmetric dimethylarginine (ADMA) and nitrogen oxide (NO) in patients on maintenance hemod...
The use of the domestic hen as a model in developmental studies and cancer research
The main advantage of the chicken embryo as a model for developmental studies is that it is readily manipulated. This has led to major discoveries in the field of developmental biology. Many genes are found to be express...
The increasing number of patients in end-stage renal failure:<br /> A global phenomenon with serious consequences <br /> <br />
The number of patients in renal replacement therapy (RRT) with hemodialysis (HD), peritoneal dialysis (PD) or renal transplantation (RTx) has increased dramatically over the past decades. Although the rate of increase in...
Neurofibroma
NO abstract available
Pulmonary Langerhans' cell histiocytosis or miliary tuberculosis? Case report and literature review
Early stage pulmonary Langerhans' cell histiocytosis (PLCH) can convincingly mimic miliary tuberculosis (TB), clinically, radiologically, functionally and on histopathological examination, and conversely miliary TB may b...