Admission serum glucose level as a marker of outcome severe head injury patients
Journal Title: Indian Journal of Neurosciences - Year 2018, Vol 4, Issue 4
Abstract
Introduction Hyperglycemia is a one of the common response to stress especially when it is related to the tissue injury like head injury The purpose of this study was to detect the effect of admission hyperglycemia on the overall mortality and morbidity in the patients of severe head injuryMaterials and Methods Retrospective methods were used in this study and this study includes patients with severe TBI The patients were divided into two groups Hyperglycemia group and normal blood sugar level group This was based on the serum glucose level The Outcome measures of the study were mortality and Glasgow Outcome Scale which were recorded at 6 monthsResults A total of 160 patients male 112 female 48 were included in this study who had severe TBI and also met the inclusion criteria The mean SD age of the patients taken for this study was 465 115 years The mean GCS of the patients at the time of admission was 52 15 The mean SD serum glucose level within 24 hours of admission was 249 mgdL with lowest being 110 mgdL and highest of 390 mgdL Fiftyfive 34 patients had hyperglycemia glucose level 200mgdL at admission and remaining 105 patients 66 had normal serum magnesium levels Hyperglycemia resulted in 55 of the total mortality N 30 compared to 38 N40 in patients who had normal blood glucose level after 24 hours of admission The mortality rate is significantly higher in patients with hyperglycemia 2 368 P 004 The assessment of the patients with Glasgow outcome score was done at 6 months follow up 80 N44 of the patients who had high blood sugar levels showed the poor Glasgow outcome compared to the patients with normal blood glucose where 66 N65 which was statistically significant 2 544 p 019Conclusion Hyperglycemia at admission increases the rate of mortality and morbidity in head injury patientsKeywords Hyperglycemia Severe head injury Glasgow outcome scale
Authors and Affiliations
Bhagwati Salgotra, Raghavendra Nayak, Dhruv N. Patel, Marci Juneja, Deval Patel
Keywords
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- EP ID EP490491
- DOI 10.18231/2455-8451.2018.0048
- Views 77
- Downloads 0
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