Advances and challenges in eliminating mother-to-child transmission of hepatitis B virus worldwide
Journal Title: Journal of Clinical Hepatology - Year 2024, Vol 40, Issue 11
Abstract
At present， there are policies for hepatitis B testing in 89.8% of countries and regions around the world. In 2022， the global hepatitis B vaccine birth dose coverage reached 45%， while the third-dose coverage reached 85%. Approximately 3% of pregnant women with high viral loads have received antiviral therapy， and the prevalence rate of HBsAg is about 0.7% among children aged≤5 years. While significant progress has been made in various countries towards eliminating mother-to-child transmission of hepatitis B virus （HBV）， there are still large gaps across countries and numerous challenges. There are differences in the prevalence of hepatitis B， vaccination， and access to antiviral drugs across the globe， and in addition， the factors such as insufficient laboratory testing capacity and difficulties in ensuring sustained access to treatment among pregnant and parturient women with HBV infection pose obstacles to eliminating the mother-to-child transmission of HBV.
Authors and Affiliations
Hongqiao ZHENG, Ailing WANG
Keywords
Related Articles
- EP ID EP753514
- DOI 10.12449/JCH241104
- Views 31
- Downloads 1
Effect of interleukin-22 on hepatic stellate cell activation and its mechanism
[Objective] To investigate the effect of interleukin-22 （IL-22） on the activation of hepatic stellate cells （HSCs） and its mechanism. [Methods] The human HSC LX-2 cells were selected for the study， and the LX-2 cell...
Research advances in traditional Chinese medicine syndromes of fatty liver disease
Fatty liver disease can be classified into alcoholic fatty liver disease and nonalcoholic fatty liver disease based on etiology， and it has become the most important liver disease worldwide. Due to the differences in th...
Molecular mechanism of lenvatinib resistance in hepatocellular carcinoma
Hepatocellular carcinoma is the most common malignancy of the liver and poses serious health burdens on China and the whole world. However， most patients with hepatocellular carcinoma are already in the advanced stage a...
Influence of serum cumulative triglyceride exposure on the risk of acute pancreatitis
[Objective] To investigate the association between cumulative triglyceride （cumTG） exposure and the risk of acute pancreatitis （AP）. [Methods] A prospective study was conducted for a cohort of 56 883 workers from Kai...
Current status of the application of artificial intelligence in the diagnosis and treatment of pancreatic cancer
Pancreatic cancer is a common malignant tumor of the digestive system， with a low early diagnosis rate， a high surgical mortality rate， a low cure rate， and a poor overall prognosis. In recent years， with the contin...