Advances in Microscopy-A Review
Journal Title: Voyager - Year 2017, Vol 0, Issue 1
Abstract
Biological microscopy has undergone a revolution in last two decades. Light microscopy is a mainstay of modern molecular, cell and developmental biology laboratories and spans applications in basic research, preclinical and recently even clinical domains. Electron microscopy is also growing with various changes. Rapid developments at all levels of microscopy experiments – from improvements in sample labelling, contrast, illumination, resolution, signal detection and data processing have all occurred and there is every reason to expect that these advances will simply continue. Applications for these new imaging methodologies are also growing. Combining these technical advances with robotics has resulted in automated microscopes suitable for screening small molecule libraries for drug discovery and recording cell phenotypes that result from systematic gene knockdown by RNA interference or tissue phenotypes caused by diseases. Present review summarizes the historical developments in the microscopy technique. It also highlights the advancements in the technique and its myriad applications.
Authors and Affiliations
Neetu Nimesh, Deepali Joon, Manoj Nimesh
Keywords
Related Articles
- EP ID EP511156
- DOI -
- Views 117
- Downloads 0
Mangroves: Afforestation and Sanctuaries
Mangrove is group of typical tropical and specialized trees growing in the saline and brackish water system. India has approximately 700,000 ha of area covered by mangroves along the estuaries and major deltas. The mangr...
A Review on the Impact of Heavy Metals on different Organs of Fishes
Environmental pollution is a universal problem throughout the world.The purpose of this review was to check the levels and accumulation of heavy metals like Cr, Cd, Zn and Pb in the various organs of fishes like liver, g...
Advances in Microscopy-A Review
Biological microscopy has undergone a revolution in last two decades. Light microscopy is a mainstay of modern molecular, cell and developmental biology laboratories and spans applications in basic research, preclinical...
Taxonomic Identification of Leidynema appendiculata using Large Subunit (28S) ribosomal DNA Sequence
Molecular markers have often been used for taxonomic identification and phylogenetic analyses in different species groups. Evolution of rDNA is relatively independent of changes in morphology, and analyses of these genet...
Haematological Modulation in W.L.H. Chicks during Passive Immunization
Hematological studies were carried out in W.L.H. chicks infected with embryonated A. galli eggs, treated with cadmium acetate and immunized with bursal, thymic and spleenic cells. Haemoglobin and total erythrocyte count...