Advances in research of the structural gene characteristics of the aflatoxin biosynthetic gene cluster
Journal Title: Journal of Plant Science and Phytopathology - Year 2018, Vol 2, Issue 3
Abstract
Aflatoxins, produced by Aspergillus spp., are strongly toxic and carcinogenic fungal secondary metabolites. Aflatoxin biosynthesis is a complex process and involves at least 30 genes clustered within an approximately 75 kB gene cluster. In this paper, we reviewed current status of the researches on the characterized structural genes involved in aflatoxin biosynthesis and their roles in aflatoxin-producing fungi, especially in A. flavus and A. parasiticus, which will improve our understanding of the mechanism of aflatoxin biosynthesis and regulation and provide reference for further study.
Authors and Affiliations
Z He, Q Li
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