Advances in traditional Chinese medicine for liver disease therapy in 2020
Journal Title: Traditional Medicine Research - Year 2021, Vol 6, Issue 3
Abstract
Liver diseases are gradually becoming a serious threat to human health worldwide. Although a number of medications have been introduced for the prophylaxis, diagnosis, and treatment of liver diseases, several limitations and challenges remain. Traditional Chinese medicine is frequently used to treat liver diseases and well known to protect hepatocytes and inhibit inflammation, oxidative stress, and fibrosis. However, given the complex composition of traditional Chinese medicine, clarifying the mechanisms behind its curative and protective effects is difficult. In this review, research progress on traditional Chinese medicine for the treatment of liver diseases in 2020 is summarized on the basis of the literature available in the PubMed database. Herbal extracts derived from traditional Chinese medicine, including flavonoids, polysaccharides, saponins, and alkaloids, and Chinese medicinal formulas, such as the classic decoctions Chaihu Shugan powder, Linggui Zhugan decoction, and Huanglian Jiedu decoction, have shown promising therapeutic efficacy in liver disease treatment. We summarized the findings of several studies on the active ingredients of traditional Chinese herbs used for liver disease treatment in 2020, focusing mainly on their ability to confer antiviral effects to treat hepatitis, regulate antioxidant levels and apoptosis to treat liver injury, inhibit inflammation and improve dysfunctions in amino acids and energy metabolism to treat alcoholic liver disease, reduce hepatic lipid deposition to treat nonalcoholic fatty liver disease, promote activated hepatic stellate cells to treat liver fibrosis, inhibit the proliferation or promote the apoptosis of liver cancer cells to treat hepatocellular carcinoma, and improve bile acid metabolism to treat cholestasis.
Authors and Affiliations
Lu Yang, Jia-Bao Liao, An-Qi Liu, Xi Chen, Fei Qu, Huan-Tian Cui, Jing Miao
Keywords
Related Articles
- EP ID EP693638
- DOI 10.12032/TMR20210316225
- Views 108
- Downloads 0
Explore the medication rules of Chinese medicine of Professor Huang Wenzheng for the treatment of chronic kidney disease based on data mining
The study found the backbone network and three-level network of the Chinese medicine for the treatment of CKD by homogeneous network analysis. The 5 top commonly used herbs were Dan Shen (Radix Salviae Miltiorrhizae) , F...
The coastal medicinal plant Vitex rotundifolia: a mini-review on its bioactive compounds and pharmacological activity
Humans have long used natural remedies like plants and herbs to treat disease. Furthermore, research has been ongoing to find alternative pharmaceutical drugs based on traditionally used plants, as natural products show...
Effects of acupuncture treatment for irritable bowel syndrome: a systematic review and meta-analysis
his article has selected a variety of major medical retrieval system. Based on the Meta-Analysis of the 17 documents, the effect of different types of acupuncture on irritable bowel syndrome in 4 evaluation criteria was...
TMR:A new star for the research of traditional medicine
After several years of preparation, we are excited that Traditional Medicine Research (TMR), an electronic English international academic journal in the field of traditional medicine, is now being launched. As one of the...
Investigation of the processing technology and mechanism of Kansui radix by licorice based on response surface methodology and integrative pharmacology
Background: The herbs should be processed by different methods before use, and the efficacy and toxicity of Chinese herbal medicines may change, which may enhance efficacy and reduce toxicity after processing. Gansui (Ka...