Advantages of COVID-19 vaccine in the T cell immune response
Journal Title: Shanghai Journal of Preventive Medicine - Year 2024, Vol 36, Issue 4
Abstract
Objective To illustrate the mechanism of COVID-19 vaccine in the T cell immune response.Methods Based on the characteristics of T cell and B cell immune response， we matched the data of incubation periods across the SARS-CoV-2 prototype strain， Delta variants， and Omicron variants and effectiveness of mRNA and inactivated COVID-19 vaccines for analysis.Results The effectiveness of mRNA COVID-19 vaccine against infection and onset was consistent with incubation period principally being ≥5 days. In contrast， the effectiveness of inactivated COVID-19 vaccine was consistent with incubation period principally being ≥8 days.Conclusion It may be interpreted by faster T cell immune response stimulated by mRNA vaccine， compared to B cell immune response by inactivated vaccine.
Authors and Affiliations
ZHUO Jiatong,
Keywords
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