Aerobic bacterial profile of blood stream infections and its antimicrobial sensitivity pattern in tertiary care hospital
Journal Title: Indian Journal of Microbiology Research - Year 2017, Vol 4, Issue 4
Abstract
Introduction: Blood stream infections cause significant disease and death worldwide and are among the most common healthcare associated infections. Large numbers of cases of treatment failure are being reported due to emergence of drug resistance. Early microbiological diagnosis and determination of antimicrobial sensitivity pattern have been shown to improve treatment outcome. The present study was aimed to determine the bacterial and antimicrobial sensitivity pattern of blood stream infections in a major tertiary care hospital. Materials and Method: Prospective cross sectional study was carried out in the Department of Microbiology, People’s College of Medical College and Research Centre, Bhopal from July 2015 to March 2016. Non repetitive blood samples of 647 clinically suspected patients of blood stream infection were collected and processed by standard methods. Isolation and identification of organisms was done as per standard guidelines. Results: Out of 647 blood culture samples, 106 (16.38%) were positive. The present study showed a predominance of Gram negative bacteremia (55.66%) over Gram positive bacteremia (44.34%). Conclusion: Appropriate treatment of blood stream infections should be based on the current knowledge of bacterial resistance pattern as provided by microbiology laboratory. This type of study will help in formulating management guidelines and antibiotic policy for effective management and proper antibiotic therapy in patients with bacteremia.
Authors and Affiliations
Mamta Sarwariya, Kalpana Sadawarte, Atul R. Rukadikar, Tukaram Prabhu
A Study of Superficial Mycoses with its Clinical Correlation at GMERS Medical College & Hospital Valsad, Gujarat
Background: Superficial mycotic infections constitute the bulk of mycotic diseases. Superficial mycoses are limited to skin, hair, and nails. The superficial fungal infections commonly encountered are dermatophytosis, ca...
Onycomycoses; mycology and epidemiology in a tertiary care hospital in North India
Introduction: “Onychomycosis” is fungal infection of the nail which may be caused by dermatophytes, non-dermatophytes and Candida.(1) It affects toe nails more than finger nail. It may involve any part of the nail includ...
Purification and characterization of bioactive secondary metabolites isolated from soil bacteria
The search for new bioactive compounds from the natural environment has rapidly been gaining momentum with the increase in multi-drug resistant (MDR) pathogens. In the present study, the antimicrobial potential of new ba...
Speciation of Enterococcal Isolates in a Tertiary Care Hospital and Molecular Characterisation of Vancomycin Resistant Enterococci (VRE)
Background: Enterococci are gram positive cocci which reside as commensal microbial flora in gastrointestinal tract, vagina, biliary tract and male urethra. E.faecalis is the predominant species followed by E.faecium. Re...
Simplified scheme for species identification and antibiotic susceptibilities of coagulase negative staphylococci isolated from clinical specimens
Coagulase negative staphylococci (CONS) species identification is difficult for most clinical laboratories. The schemes proposed by Kloos and Schleifer is the reference method used for the identification of staphylococca...