AFB POSITIVITY IN TUBERCULAR LYMPHADENITIS AND ITS CORRELATION WITH CYTOLOGICAL PATTERNS IN A TERTIARY CARE CENTRE IN SAHARANPUR
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 30
Abstract
BACKGROUND Tuberculosis is one of the most common causes of lymphadenopathy in India. It is possible to diagnose it with the help of a minimally invasive procedure known as Fine-Needle Aspiration Cytology (FNAC) and thereby unnecessary surgical interventions can be avoided. AimThe aim of the present study was to study the cytological patterns of tuberculous lymphadenitis and to correlate the Acid-Fast Bacilli (AFB) positivity with cytological patterns and also to find out overall AFB positivity. Objectives1. To study the cytological patterns of tubercular lymphadenitis. 2. To correlate the cytological pattern with AFB positivity. 3. To find out overall AFB positivity in cytology of tubercular lymphadenitis. MATERIALS AND METHODS This is a descriptive study. We studied a total of 180 cases of tuberculous lymphadenitis. Cases were retrieved and analysed retrospectively between 2015 and 2018 for three different cytological patterns A (Epithelioid granuloma without necrosis), B (Epithelioid granuloma with necrosis) and C (Necrosis without epithelioid granuloma). Ziehl-Neelsen stain (ZN) for AFB was done in all cases. RESULTS Patterns A, B and C were observed in 36 (20%), 93 (51.6%) and 51 (28.4%) cases, respectively. AFB positivity was found in 1 (2.7%) case of pattern A, 60 (65%) cases of pattern B and 45 (88.2%) cases of pattern C. The overall AFB positivity was seen in 58.88% (106/180) cases. CONCLUSION FNAC is a minimally invasive, sensitive and safe procedure to diagnose tuberculous lymphadenitis. Study of both cytological patterns and ZN staining for AFB can improve the diagnostic yield. Whether or not granuloma is present, ZN stain must be employed whenever infective pathology is suspected.
Authors and Affiliations
Neetu Goyal, Rachna Sharma, Somya Jain
Keywords
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- EP ID EP538652
- DOI 10.14260/jemds/2018/759
- Views 63
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