Age and Gender Related Changes in the Dimensions of Corpus Callosum by MRI-In South Indian Population
Journal Title: International Journal of Anatomy Radiology and Surgery - Year 2017, Vol 6, Issue 3
Abstract
Introduction: Corpus callosum is the largest and most important commissural white matter tract connecting the two cerebral hemispheres. MRI helps in assessment of variation in its size and shape with respect to age and gender and possible implications on treatment planning. Aim: To evaluate the changes in the thickness of various parts and bending angle of corpus callosum with relation to age and gender. Materials and Methods: The thickness of various parts (rostrum, genu, body and splenium) of corpus callosum, the distance of genu from frontal pole, the distance of splenium from occipital pole and bending angle of corpus callosum were measured in 121 normal subjects (72 males and 49 females) in T1 mid sagittal images on 1.5 tesla MRI in M S Ramaiah hospitals, Bengaluru. The data was analysed using unpaired âtâ-test. Results: Thickness of various parts of corpus callosum (rostrum, genu, body and splenium) was found to be significantly more (p-value < 0.05) in the younger age group (20 â 60 years) than the older age group (>60 years). The bending angle, however was found to be significantly more (p-value < 0.05) in the older age group (> 60 years) as compared to the younger group (20 â 60 years). There was no significant difference in the above parameters with respect to gender. Also, distance of genu from the frontal pole and splenium from the occipital pole were not statistically different. Conclusion: This study showed that there was significant decrease in the thickness of different parts and increase in the bending angle of corpus callosum with age. There was however, no significant difference in relation to gender. Normative values thus obtained help in early detection and follow-up of disease processes.
Authors and Affiliations
Aditi Jain, Deepti Naik, Amulya Sundari, Ashok Kumar A
Keywords
Related Articles
- EP ID EP369737
- DOI 10.7860/IJARS/2017/27617:2293
- Views 103
- Downloads 0
Study of Ponticulus Posticus in Dry Atlas Vertebrae in Central Gujarat Region and its Clinical Significance
Introduction: Atlas is the first cervical vertebra which supports skull through atlanto-occipital joint. It has an anterior and a posterior arch with a groove on superior surface for the third part of the vertebral arter...
A Morphometric Study of Head of Radius and its Clinical Implication in Radial Head Prosthesis
ABSTRACT Introduction: The head of radius is a fundamental element for the physiological or prosthetic stability of the elbow and superior radio ulnar joint and participates with the fovea radialis in elbow flexion and w...
MR Morphometry of Lumbar Spine
Introduction: Low back pain is the second most common complaint encountered by primary care physicians. Magnetic Resonance Imaging (MRI) is the modality of choice for evaluation of low backache due to its superior soft t...
Morphological Study of Fissures, Lobes and Bronchial Pattern in the Lungs-A Cadaveric Study with Emphasis on Surgical and Radiological Implications
Introduction: Lungs are divided into lobes by the oblique and the transverse (horizontal) fissures. Knowledge about these fissures is necessary for the appreciation of lobar anatomy and for locating the bronchopulmonary...
Morphology of Extensor Indicis Proprius Muscle in the North Indian Region: An Anatomic Study with Ontogenic and Phylogenetic Perspective
ABSTRACT Introduction: Variants on muscles and tendons of the forearm or hand occur frequently in human beings. They are often discovered during routine educational cadaveric dissections and surgical procedures. Aim: To...