Age and Opportunistic Infections: Prevalence and Predictors among Older People Living With HIV
Journal Title: National Journal of Community Medicine - Year 2018, Vol 9, Issue 8
Abstract
Objectives: To document preva-lence of opportunistic infections (OI) among older people living with HIV and to assess predictors of oppor-tunistic infections among older people living with HIV. Methods: A retrospective cohort study was conducted on records of 190 alive older people living with HIV (PLHIV) aged 50 years or more on ART at ART centre, New Civil Hospital, Surat. Socio-demographic variables, WHO stage, CD4 count and OIs were studied. Statistical analysis: Data was analysed by SPSS software to calcu-late frequencies and measures of central tendencies. Logistic Regres-sion model was applied. Results: Participants mean age was 57.89 ±5.45 years, 66.84% were males. Heterosexual route was ma-jor route of HIV transmission. Prev-alence of OIs was 63.7%; with Tu-berculosis 22.1% most common, fol-lowed by ARI 17.2% and Oral can-didiasis 13.2%. Baseline WHO clin-ical stage III (OR: 8.2; CI: 2.873-23.870) and IV (OR:21.7; CI: 3.83-122.90), Baseline CD4 <200 cells/cumm (OR:3.7; CI:1.10-12.11), weight <50kg in last visit (OR:2.9; CI: 1.07-8.23)were predictors of OIs among older PLHIV. Conclusion: Low CD4 count and higher stage of disease at initiation of ART, weight <50kg in last visit are predictors for OI by Logistic Re-gression model
Authors and Affiliations
Shivangi A Inamdar, J. K. Kosambiya, Anjali Modi, Alpesh Gohil, Alap Mehta, Tinkal Patel
Keywords
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