Age – Can it be a Navigational Factor in Dengue: A Study
Journal Title: Indian Journal of Emergency Medicine - Year 2019, Vol 5, Issue 2
Abstract
Background: Dengue infections can occur as epidemics in India causing high morbidity and mortality. The awareness of risk factors can help in early recognising and treatment of severe forms and reduction in mortality. Age is one such intrinsic risk factor which can affect the outcome to a significant extent. Objective: To analyse the haematological variables affected by different age groups and its impact by comparison with other similar or clinical studies on complications of dengue. Materials and Methods: A total of 132 serologically proven Dengue positive cases were analysed along with relevant haematology data after tabulation against patients unique hospital identification number, age and sex. The data was collected over a one month period in November 2016 in Haematology Department of KIMS Hospital and Research Centre, Bengaluru. Results: Our study showed an age range between 5 months to 65 years with most patients in the 12-25 years group and an average of 32 years. We had 30% paediatric cases (≤12 years) and 70% non-paediatric cases (>12 years). The male to female ratio was 1.2:1 with a slight male predominance. The analysis of haematocrit patterns in association with age showed 70% paediatric cases with rise in haematocrit above reference range in comparison to 43% in adults. The highest haematocrit was 59.6 in adults as against to 47% in paediatric cases. Total white cell count patterns were uniform in both groups. The lowest count was noted in adults (1100 cells/cumm) as against paediatric (1900 cells/cumm) cases. The differential count showed marginal increase in lymphocytosis in non-paediatric (70%) as against paediatric (63%) cases, whereas neutrophilia (23% vs 50%) in paediatric and non- paediatric cases was more significant. Neutropenia was seen in a higher proportion of non- paediatric (38%) vs paediatric cases (18%). Platelet counts less than 1.0 lakhs/cumm was noted in 98% in non-paediatric as against 90% of paediatric cases. There was a significantly higher proportion of NS1 Antigen positivity noted in non-paediatric (34%) as against paediatric (15%). Paediatric cases had a higher association (85%) with antibody pattern as against non-paediatric (65%) cases. Conclusion: Age has a significant impact as a prognosticator in dengue and can play an important and decisive role in early diagnosis and management of severe cases.
Authors and Affiliations
Anagha Joshi A
Keywords
Related Articles
- EP ID EP630008
- DOI 10.21088/ijem.2395.311X.5219.5
- Views 93
- Downloads 0
Mortality Audit of Febrile Cases Admitted in a Tertiary Care Hospital in Eastern India
Background: Frequent outbreaks of dengue, malaria, typhoid, and influenza are very common in India, especially during the monsoon season. This study aimed at analyzing the cause and outcome of such febrile cases admitted...
Rare Presentation of Prolonged Impaction of A Button Battery in Esophagus without Life-Threatening Consequences
The diagnosis of button battery ingestion in toddler age group can be quite difficult as the patient cannot give the history himself/herself (unless it is witnessed). Such ingestion can lead to serious complications due...
Clinical Presentation of Renal Injury at a Tertiary Care Hospital
Introduction: AKI occurs predominantly in urban intensive care units and is associated with multiorgan failure and sepsis, high mortality, and occurrence in older populations. While cases of AKI in urban areas of the dev...
Reperfusion: for Better or for Worse
Introduction:Cerebral hyperperfusion, or reperfusion syndrome,is a rare, but serious, complication following revascularization. Hyperperfusion is defined as a major increase in ipsilateral cerebral blood flow (CBF) that...
Petrol Ingestion Causing Methaemoglobinaemia in Glucose 6-Phosphate Dehydrogenase (G6PD) Deficiency Patient
A 31yearold male found unconscious in his parked car on road side was admitted for evaluation and management in the hospital. The patient presented with central and peripheral cyanosis and arterial blood gas (ABG) report...