Aging of prokaryotic organisms
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2011, Vol 65, Issue 0
Abstract
Until recently it was thought that aging is a characteristic feature only of cells and organisms of eukaryotic origin. Recent studies on Caulobacter crescentus showed that their dimorphic life cycle associated with asymmetric cell division leads to a gradual increase in the time needed for the development of new bacteria generations, which may reflect aging of this organism. Moreover, as shown in Escherichia coli, accelerated exhaustion of proliferative capacity and bacteria death are caused by inheritance of certain structures from the mother cell during cell division. A similar phenomenon, called ‘conditional senescence’, has been observed during the stationary phase of growth in liquid cultures. The aim of this paper is to present the current state of knowledge on the causes, mechanisms and evolutionary significance of aging in bacteria. Some issues associated with bacterial aging will be discussed in the context of similar phenomena occurring in eukaryotic cells.
Authors and Affiliations
Marek Simon, Magdalena Waszyk-Nowaczyk, Krzysztof Książek
Keywords
Related Articles
- EP ID EP66518
- DOI -
- Views 155
- Downloads 0
Komórka na granicy życia i śmierci, czyli oddziaływania między procesami autofagii i apoptozy
Przez ostatnie kilkanaście lat zależności między autofagią i apoptozą były przedmiotem intensywnych badań. Zaburzenia każdego z tych procesów zaangażowane są w etiologię licznych chorób. Wpływ autofagii i apoptozy na fun...
Rola sfingolipidów w wybranych chorobach układu krążenia
Bioaktywne sfingolipidy uczestniczą w regulacji wielu procesów, zachodzących w komórce, takich jak jej różnicowanie, proliferacja czy programowana śmierć. Metabolizm sfingolipidów w sercu jest regulowany przez wysiłek fi...
Bioactive lipids in kidney physiology and pathophysiology
Lipids not only have structural functions, but also play an important role as signaling and regulatory molecules and participate in many cellular processes such as proliferation, differentiation, migration, and apoptosis...
Wpływ polimorfizmu genu dla receptora witaminy D (VDR) na wysokość ciała u dzieci - doświadczenia własne
The role of inflammation in colon cancer pathogenesis
The results of the latest research more and more bind development of neoplasms with the chronic inflammation. Inflammatory process creates microenvironment promoting development of neoplasms; as a result, malignant proce...