Albumen does not work: what alternative hypothesis for Starling’s capillary-interstitial transfer is there? The hydrodynamics of the porous orifice tube
Journal Title: Journal of Surgical Research and Therapeutics - Year 2018, Vol 1, Issue 1
Abstract
The news article and systematic review of randomised controlled trials analysing the results of colloids versus crystalloids use in resuscitating the critically ill patients [BMJ 2004;328:852] is informative. The respected members of Cochrane Injuries Group Albumin Reviewers concluded: “There is no evidence that albumin administration reduces mortality in critically ill patients with hypovolaemia, burns, or hypoalbuminaemia and a strong suggestion that it may increase mortality”. I urge this group and all concerned not only to “urgently review the use of plasma proteins in resuscitating the critically ill patients” but also to investigate the scientific basis on which it was advocated in the first place. The documented evidence supporting these issues and implications are highlighted here
Authors and Affiliations
Ahmed N. Ghanem
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