Alfentanil in Elective Caesarean Sections under General Anaesthesia: Maternal Haemodynamic Changes Due to Intubation
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2017, Vol 4, Issue 2
Abstract
Background: Opioids administered before caesarean section under general anaesthesia reduce maternal stress response related to intubation and surgery but may decrease the Apgar score after delivery and when opioids are used. Aim: effect of low dose of shortacting opioid alfentanil on haemodynamic changes due to tracheal intubation during general anaesthesia for caesarean sections. Materials and Methods: Patients were taken for a period of 2 years in 60 pregnant patients between the ages of 18 and 40 years, scheduled for elective caesarean section, were assigned to two equal groups. GroupA:(N=30) Received alfentanil 10 mg/kg, diluted in normal saline (total volume of 10 ml), GroupP:(N=30) Received 10 ml normal saline as placebo for premedication. Results: There were no significant statistical differences among the two groups regarding age, weight, BIS and maternal preoperative haemodynamic parameters. Following alfentanil administration, systolic blood pressure decreased at 1, 5 and 10 min after endotracheal intubation. Diastolic blood pressure decreased only 1 min after intubation and heart rate decreased 1 and 5 min after intubation. There were significant statistical differences between the two groups in regard to mean heart rate 1 min after induction of anaesthesia (P = 0.01), 1 min after endotracheal intubation (P = 0.000) and 5 min after endotracheal intubation (P = 0.04). Mean BIS values were not significantly different between the two groups (P = 0.3). Mean of neonatal Apgar scores at 1 and 5 min and neonatal SpO2 were not significantly differerent between the two groups . Conclusion: Alfentanil as premedication decreased maternal systolic, diastolic blood pressure and heart rate in the 1st min of general anaesthesia for caesarean sections.
Authors and Affiliations
Srinivas Rapolu
Keywords
Related Articles
- EP ID EP464654
- DOI 10.21088/ijaa.2349.8471.4217.1
- Views 94
- Downloads 0
A Comparative Study Between Ultrasound and Peripheral Nerve Stimulator Guided Supraclavicular Brachial Plexus Block in Adult Patients for Elective Upper Limb Orthopaedic Surgeries
Background: There are many advantages of ultrasound guided supraclavicular brachial plexus block over the peripheral nerve stimulator guided supraclavicular brachial plexus block. Ultrasonography allows the operator to v...
A Prospective Randomized Comparative Study of Epidural Block and General Anesthesia for Percutaneous Nephrolithotomy for Hemodynamic Stability and Postoperative Analgesia
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure for removal of calculi in pelvicalyceal system which is usually performed under general anaesthesia. We conducted a prospective, randomized, comparati...
Effect of Posture on Postoperative Oxygen Saturation in Patients Undergoing Upper Abdominal Surgery under General Anaesthesia: It Matters
Context: Incidence of postoperative pulmonary complications is between 3050% in patients undergoing abdominal surgery. Addressing pain at surgical site and improving respiratory mechanics , to reduce postoperative hypox...
Are We Performing Hand Hygiene: A Lifesaving Skill Correctly?
This question is asked invariably just like being asked during CPR’s correct method and right timing of practicing hand hygiene to avoid a loss of life to hospital acquired infection (HAI). Are we doing enough? Are we re...
Comparison of Proseal Laryngeal Mask Airway Versus Endotracheal Tube in Anaesthetized Adult Patients
Endotracheal tube (ETT) is always considered as a standard device to keep an airway patent during surgery. Airway management of patients has also progressed form endotracheal tube to lesser invasive laryngeal mask airway...