Alport Syndrome in Kenya: Case Reports and Literature Review
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 12
Abstract
Alport syndrome (AS) is an inherited disorder of basement membranes. It results from mutations affecting specific proteins of the type IV (basement membrane) collagen family. This condition affects the kidneys, the eyes, the hearing, among others. The renal component of the Alport syndrome manifests as hematuria and/or proteinuria, with progressive chronic renal failure, while the ears involvements presents occasionally as high-tone sensorineural hearing loss. The condition manifests with progressive impairment of the affected organs. Renal failure is a major manifestation .Early diagnosis and symptomatic management are key especially in delaying the renal failure. There is paucity of data from Africa about Alport syndrome. We present three cases managed in our hospitals in Kenya, East Africa, literature review and treatment
Authors and Affiliations
Samuel K. Kabinga, Doris W. Kinuthia
Keywords
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- EP ID EP421686
- DOI 10.9790/0853-1712050105.
- Views 63
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