Alterations in carbohydrate metabolism under cryptorchid condition in albino rats
Journal Title: Journal of Applied and Natural Science - Year 2009, Vol 1, Issue 1
Abstract
Bilateral cryptorchidism was induced surgically in adult wistar strain albino rats and the carbohydrate metabolic pathway has been studied in testis, and sex accessory organs of both control and cryptorchid animals by estimating the marker enzymes and the substrates of the metabolism. In cryptorchid animal tissues, accumulation of lactic acid and glycogen was observed with inhibited phosphorylase activity in comparison to the controls. The reproductive tissues like testis, epididymis, prostate gland and seminal vesicles had shown remarkable elevation in the glycogen content, which can be attributed to decreased phosphorylase activity. In view of androgen dependent nature of phosphorylase its inhibition can be correlated to decreased testosterone circulation in the body. Consequently the free glucose content of the tissues was markedly decreased suggesting a decrease in the mobilization of the carbohydrates into energy metabolism. All the reproductive tissues had shown significant accumulation of lactic acid with inhibited oxidative enzyme activities. Thus the reproductive tissue oxidative metabolism had been suppressed during cryptorchidism leading to a shift towards glycolysis and creating a situation of functional suppression.
Authors and Affiliations
K. Varma, E. Madhuri, S. Basha, Y. Radha Madhavi, M Sekhar, M. Bhaskar
Keywords
Related Articles
- EP ID EP126236
- DOI -
- Views 97
- Downloads 0
GIS based modeling using Analytic Hierarchy Process (AHP) for optimization of landfill site selection of Rohtak city, Haryana (India)
Landfills are the most common method for the disposal of municipal solid waste the world over, as well as in India due to their low technical and economic requirements. The selection of an appropriate site for the establ...
Induction of reactive oxygen species in brain of Etroplus maculatus after exposure to bisphenol A
The present study was aimed to investigate that bisphenol A, an environmental estrogen, exposed at 648 μg/ L concentration for 96 h could induce reactive oxygen species in brain of cichlid fish, Etroplus maculatus. Evalu...
Influence of arbuscular mycorrhizal fungi and Trichoderma viride on growth performance of Salvia officinalis Linn.
Salvia officinalis (Sage) is a popular kitchen herb, member of mint (Lamiaceae) family has been cultivated for its wide range of medicinal values. Arbuscular mycorrhizae (AM) are beneficial symbionts for plant growth and...
Eco-friendly management of anthracnose of chilli caused by Colletotrichum capsici
The anthracnose of chilli caused by Colletotrichum capsici is a widespread problem limiting the profitable cultivation and seed production of chilli throughout the major chilli growing regions of India. Four isolates (SC...
Biopesticidal effect of leaf extract of neem (Azadirachta indica A. Juss) on growth parameters and diseases of tomato
This paper investigates the potential use of neem (Azadirachta indica A. Juss) aqueous leaf extract on the growth, yield and disease control of a common vegetable plant tomato (Solanum lycopersicum L.). The neem extract...