Aluminium phosphide poisoning in children -challenges in diagnosis and management
Journal Title: Scholars Academic Journal of Biosciences - Year 2014, Vol 2, Issue 8
Abstract
Metal phosphides in general and aluminium phosphide in particular are potent insecticides and rodenticides. These are commercially used for protection of crops during storage, as well as during transportation. They are highly toxic substances and its poisoning is a common pediatric emergency leading to mortality and morbidity in children. Thousand of innocent children are poisoned accidentally every year throughout the world mainly due to their innovative and exploratory nature and mouthing tendency. Following the ingestion of metal phosphide, phosphine gas is generated which is rapidly absorbed throughout the gastrointestinal tract, reaches the blood stream and causes multisystemic involvement We tried to review the various aspects of toxicity associated with aluminium phosphides, including clinical presentation specially unusual presentation ,diagnostic and management challenges and poor prognostic indices. The presentation varies from GIT manifestation to shock, cardiac arrhythmias, renal failure, metabolic acidosis and rare presentation pleural effusion, ascites, pericarditis, acute respiratory distress(ARDS). Diagnosis is based on clinical suspicion, history of ingestion, clinical manifestations with garlic or decaying fish odour, unexplained shock .A range of chemical tests and analytical methods may be used for the analysis of sample like silver nitrate impregnated paper test on the gastric fluid of patients, a reliable and sensitive method to detect phosphine In management role of magnesium sulphate (MgSo4.) in reducing the cardiac arrhythmias and mortality is well documented.
Authors and Affiliations
Sunita Koreti, Yogendra. S. Verma, Nitin Prasad, G. S. Patel, Neelam Rajput
Keywords
Related Articles
- EP ID EP377866
- DOI -
- Views 110
- Downloads 0
Plant Names in Sanskrit: A Comparative Philological Investigation
Philological study helps trace genesis and development of names. Present study is aimed at revealing Sanskrit plant names in philological perspective. The same plants are also studied on the similar line having common na...
Main diseases of safflower (Carthamus tinctorusL.) in Uzbekistan
In Uzbekistan the disease of rust in safflower is widely spread. Furthermore, safflower is being partially diseased with Fusarium wilt, Alternaria and Ramularia leaf spots. It is important to carry out agro-technical is...
The Post-Mortem Diagnosis of Vaso occlusive Crisis in Sickle Cell Disease in a Previously Undiagnosed Sickle Cell Disease Of An Asymptomatic Adult – A Case Report
Abstract: Sickle haemoglobin is highly prevalent in central region of India. It has variable clinical presentation and most of the Indian patients remain asymptomatic for longer period of time. Less numbers of deaths due...
Estimation of lead in blood donors: Removal of lead associated with blood transfusion using carboxymethyl cellulose
Abstract: Lead is well known for centuries for its toxic effects on adults and children through its different routes of exposure. In this study we gave our concern on lead levels of the blood donors to evaluate the possi...
The craniometrical study of orbital base of Indian population and its applied importance
Abstract: In Norma frontalis the orbital base appear equal. But dimensionally are they equal or different? By considering orbital index as reference measure this study was conducted to evaluate the significant variation...