Amino-Terminated Generation 2 Poly(amidoamine) Dendrimer as a Potential Broad-Spectrum, Nonresistance-Inducing Antibacterial Agent

Journal Title: The AAPS Journal - Year 2013, Vol 15, Issue 1

Abstract

The online version of this article (doi:10.1208/s12248-012-9416-8) contains supplementary material, which is available to authorized users.

Authors and Affiliations

Xiaoyan Xue, Xiaoqing Chen, Xinggang Mao, Zheng Hou, Ying Zhou, Hui Bai, Jingru Meng, Fei Da, Guojun Sang, Yukun Wang, Xiaoxing Luo

Keywords

Related Articles

In Vivo Quantification of Active Decitabine-Triphosphate Metabolite: A Novel Pharmacoanalytical Endpoint for Optimization of Hypomethylating Therapy in Acute Myeloid Leukemia

Decitabine (DAC) is used for treatment of patients with myelodysplastic syndromes and acute myeloid leukemia (AML). Following cellular uptake, DAC is activated to DAC-triphosphate (TP) and incorporated into DNA. Once inc...

Enhancement of MHC-I Antigen Presentation via Architectural Control of pH-Responsive, Endosomolytic Polymer Nanoparticles

The online version of this article (doi:10.1208/s12248-014-9697-1) contains supplementary material, which is available to authorized users.

Release and permeation kinetics of caffeine from bioadhesive transdermal films

The aim of this work was to investigate, in vitro, the kinetics of release and permeation of caffeine, chosen as model drug, from bioadhesive transdermal films. These films are not self-adhesive but become adhesive when...

AAPS Workshop Report: Strategies to Address Therapeutic Protein–Drug Interactions during Clinical Development

Therapeutic proteins (TPs) are increasingly combined with small molecules and/or with other TPs. However preclinical tools and in vitro test systems for assessing drug interaction potential of TPs such as monoclonal anti...

Download PDF file
  • EP ID EP681755
  • DOI  10.1208/s12248-012-9416-8
  • Views 97
  • Downloads 0

How To Cite

Xiaoyan Xue, Xiaoqing Chen, Xinggang Mao, Zheng Hou, Ying Zhou, Hui Bai, Jingru Meng, Fei Da, Guojun Sang, Yukun Wang, Xiaoxing Luo (2013). Amino-Terminated Generation 2 Poly(amidoamine) Dendrimer as a Potential Broad-Spectrum, Nonresistance-Inducing Antibacterial Agent. The AAPS Journal, 15(1), -. https://europub.co.uk/articles/-A-681755