An autoimmune polyglandular syndrome complicated with celiac disease and autoimmune hepatitis
Journal Title: Annals of Hepatology - Year 2016, Vol 15, Issue 4
Abstract
Autoimmune polyglandular syndrome (APS) is a combination of different autoimmune diseases. The close relationship between immune-mediated disorders makes it mandatory to perform serological screening periodically in order to avoid delayed diagnosis of additional autoimmune diseases. We studied a patient with type 1 diabetes (T1D) who later developed an autoimmune thyroid disease (ATD) and was referred to our hospital with a serious condition of his clinical status. The patient was suffering from an advance stage of celiac disease (CD), the delay in its diagnosis and in the establishment of a gluten-free dietled the patient to a severe proteincalorie malnutrition. Later, the patient developed an autoimmune hepatitis (AIH). We consider that clinical deterioration in patients with APS should alert physicians about the possible presence of other immune-mediated diseases. Periodic screening for autoantibodies would help to prevent delayed diagnosis and would improve patient’s quality of life.
Authors and Affiliations
Romina Dieli-Crimi, Concepción Núñez, Lourdes Estrada, Natalia López-Palacios
Keywords
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- EP ID EP78605
- DOI 10.5604/16652681.1203162
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