An Echocardiographic evaluation of left ventricular diastolic dysfunction in asymptomatic, normotensive patients with type 2 diabetes mellitus at tertiary centre
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Abstract: Diabetes Mellitus is a disease with multi-system complications. Left ventricular diastolic dysfunction (LVDD) represents the first stage of diabetic cardiomyopathy preceding changes in systolic function, reinforcing the importance of early examination of ventricular function in individuals with diabetes mellitus (DM). Doppler echocardiography is reliable noninvasive means to assess early diastolic dysfunction.The aim is to study the prevalence of LV diastolic dysfunction in asymptomatic, normotensive patients with diabetes mellitus.A study was carried out on 50 normotensive diabetic patients and compared with 50 age and sex matched controls. In all the patients, detailed history, physical examination and specific investigations (conventional Doppler echocardiographyat rest) were done to find out the prevalence of diastolic dysfunction.The study group of 100 patients were of age 30-55years, 50 type 2 diabetic patients and 50 non-diabetic controls had 32 males and 18 females in both the groups respectively. Among 50 Type 2 DM cases 29 (58%) had LV diastolic dysfunction. Out of 32 males, 20 males (62.5%) and out of 18 females, 9 females (50%) had diastolic dysfunction. LVDD is common in patients with type 2 DM even in normotensive patients independent of confounding effect of hypertension, ischemia and BMI. We conclude that early diagnosis and institution of treatment will reduce morbidity andimprove the outcomes, and prevent future heart failure. Keywords:LVDD (left ventricular diastolic dysfunction), DM (diabetes mellitus), Doppler echocardiography, E/A ratio
Authors and Affiliations
Rajendrakumar P, Kirankumar Meti
Keywords
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