An efficient synthesis of new benzohydrazide and 1, 3-thiazine fused s-triazines as potential antimicrobial agents
Journal Title: Journal of Pharmaceutical and Biological Sciences - Year 2018, Vol 6, Issue 1
Abstract
As a part of our endeavor toward the synthesis of new heterocyclic bioactive agents some new substituted 135 triazine derivatives with 4nitrobenzohydrazide and 64methoxyphenyl4phenyl6H13thiazin2amine and substituted thiourea were reacted and evaluated for their in vitro antimicrobial activity against Gram positive and Gram negative strains using a micro dilution procedure Synthesized compounds T1GE to T15GE showed to be effective with MIC microgmL among them T5GE T8GE T9GE and T14GE showed excellent activity against a panel of microorganisms The newly synthesized compounds were characterized using IR 1HNMR 13CNMR MASS AnalysisKeywords Cyanuric Chloride 4nitrobenzohydrazide 64methoxyphenyl4phenyl6H1 3thiazin2amine Different thiourea derivatives and antimicrobial activity
Authors and Affiliations
G. M. Malik, T. V. Patel
Keywords
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- EP ID EP512454
- DOI 10.18231/2320-1924.2018.0006
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