An Epidemiological Study of Cases of Urothelial Carcinoma of Urinary Bladderin a Tertiary Care Centre
Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2013, Vol 2, Issue 1
Abstract
Background: Urinary bladder cancer is the fourth most common malignancy in Western world. It is a heterogeneous disease with variable natural history. There is paucity of data in our country. Aims and Objectives: The present study aims to assess the risk factors contributing to urothelial carcinoma of bladder in the southern region of West Bengal and histopathological grading (WHO/ISUP). Materials and Methods: It was a retrospective study by multivariate analysis of case record proforma (CRP), agreed upon by a team of experts from the departments of Urosurgery and Pathology,CNMC & H, Kolkata from December, 2007 to November, 2009. Total 88 subjects who had attended in the department of urosurgery and already been diagnosed either by cystoscopic biopsy or Transurethral Resection of Bladder Tumour (TURBT), were enrolled. Results: There was male preponderance (86.4 % male vs 13.6% female); the age range being 30-81 years (median 65). Hindus (81.8 %) were affected more compared to Muslims (18.2 %). Blood group analysis showed highest incidence in B group (41%) followed by O (32%). Tobacco smoking (75% cases) revealed a strong relationship with bladder cancer and that was quantity and duration dependant. Less water intake (53.4%) and poor socioeconomic status (82%) were significant contributory factors. Analysis of occupational factors gave no epidemiological clue. Histopathological Examination (HPE) revealed low grade urothelial carcinoma (51cases), high grade (24 cases) and papilloma with low malignant potential (13 subjects). Conclusion:Proper epidemiological survey plays a pivotal role in bladder cancer to validate it in the disease control programme.
Authors and Affiliations
Ranu Roy Biswas , Sristidhar Mangal , Debasish Guha , Keya Basu , Dilip Karmakar
Keywords
Related Articles
- EP ID EP119966
- DOI -
- Views 89
- Downloads 0
Cytokine Expression in Homozygous Sickle Cell Anaemia
Background: Sickle cell anaemia is an inherited disease in which the red blood cells become rigid and sticky, and change from being disc-shaped to being crescent-shaped. The change in shape is due to the presence of...
Identification of Practical Pharmacology Skills Useful for Good Clinical Practice
Background: Awareness about animal ethics is increasing everywhere. This increased awareness coupled with strict regulations discouraging the use of animals for routine experiments have tied the hands of many pharmacolog...
Bilateral Tubercular Lung Abscess in a Diabetic Female
Liquefactive necrosis of the lung tissue caused by microbial infection, lung abscess is characterised by formation of cavities containing necrotic debris. In the vast majority of cases of lung abscess, polymicrobial bact...
Assessment of Prognosis in Cranio Cerebral Trauma Based on Findings on First CT Scan
Background: Traumatic Brain Injuries (TBIs) are a leading cause of morbidity, mortality, disability and socioeconomic losses in India and other developing countries. The first Computed Tomography (CT) scan of TBI pat...
Genito-Urinary Infection in an Adult Male Caused By Group B Streptococcus
Streptococcus agalactiae, Group B Streptococcus (GBS) has been considered to be a major pathogen in neonates and pregnant women.GBS disease in non- pregnant adults is increasing, particularly in elderly persons and those...