An Exceptional Triple Endocrinopathic Disorder; Schmidt’s Syndrome in a Dog
Journal Title: Turkish Journal of Veterinary Internal Medicine - Year 2022, Vol 1, Issue 1
Abstract
Comorbid, Endocrinopathy, Hypothyroidism, Polyglandular Adenopathy Polyglandular deficiency syndromes result from multiple endocrine failures and describe a combination of two or more organ-specific autoimmune disorders. Endocrine disorders may sometimes be deceptive, as a diagnosis of one failure may lead to a false satisfaction of the case, despite the resistance to treatment. The present case describes the Schmidt syndrome of a twelve-year-old, intact female mixed breed dog previously diagnosed with hypoadrenocorticism and inadequate response to treatment. Hypothyroidism and diabetes mellitus were diagnosed with a positive Antinuclear Antibody test. The treatment was initiated, resulting in clinical improvement with the absence of lethargy and seizures in a couple of days, and metabolic values returned to normal limits in two weeks. This is the first case of Schmidt syndrome (Polyglandular Adenopathy type 2) with triple endocrinopathy in a dog presenting immune intervention. We underline that the comorbid endocrinopathies with probable immune etiology must be considered in canine patients with suboptimal response to treatment for hypothyroidism or hypoadrenocorticism.
Authors and Affiliations
Başar Ulaş SAYILKAN Emre KÜLLÜK Yücel MERAL Duygu DALĞIN
Keywords
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- EP ID EP711347
- DOI https://doi.org/10.5281/zenodo.7473106
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