AN INSIGHT TO THE SYNTHETICALLY OBTAINED TRIAZOLE POSSESSING NUMEROUS BIOLOGICAL ACTIVITIES
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 9
Abstract
Heterocyclic chemistry is fundamental to biology and medicine. It is not implausible to say that we are living in the age of heterocyclic chemistry. It constitutes a large group of organic molecules exhibiting a wide range of biological activities which is the basis of life and society. The majority of pharmaceutical products that mimic natural products with biological activity are heterocyclic in nature. Azoles, five-membered heterocyclic compounds with two or three nitrogen atoms, constitute a large group of organic substances exhibiting a wide range of biological activities. Triazole, a five-membered azole nucleus composed of three nitrogen atoms and two carbon atom is found to possess enormous biological activity such as anti-HIV, anti-HBV, antibacterial, antitumor, anti-inflammatory, antiviral, CNS stimulant, antifungal and antituberculosis activities. Moreover, triazole nucleus is found in many drugs such as anastrozole, estazolam, ribavirin and triazolam. Here in this review article we have reported the recent development in the pharmacological activity of some newly synthesized triazole derivatives.Â
Authors and Affiliations
Mohammad Arshad
Keywords
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