An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells
Journal Title: Translational Research in Urology - Year 2020, Vol 2, Issue 3
Abstract
Intravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that produce an artificial T-cell receptor for use in immunotherapy. Chimeric antigen receptors are receptor proteins that have been engineered to give T cells the new ability to target a specific protein Its effect is mostly achieved using activating the immune system; the same mechanism proposed likely for chimeric antigen receptor (CAR) T cells. Hence CAR-T cell therapy could be considered for bladder cancer treatment.
Authors and Affiliations
Seyed Saeed Tamehri Zadeh; AhmadReza Rezaeian
Keywords
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- EP ID EP704206
- DOI 10.22034/TRU.2021.266267.1057
- Views 75
- Downloads 0
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