An Investigation into the Pattern of Antibiotic Resistance of Bacteria Causing Ventilator – Associated Pneumonia in ICU
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 19, Issue 7
Abstract
Aims: The present study sought to determine the pattern of antibiotic resistance of pathogens in Ventilator–Associated Pneumonia (VAP) and to investigate risk factors of multi-drug resistant (MDR) in ICUs of tertiary referral hospitals. Study Design: Cross sectional study. Place and Duration of Study: In this cross sectional study, the files of 196 patients with VAP hospitalized in ICU of tertiary referral hospitals in 2014 were examined. Methodology: In order to determine common pathogens and their pattern of antibiotic resistance, the patients’ results of culturing Bronchoalveolar fluid were examined. The agent pathogens were divided in two groups of with and without MDR and different demographic and risk factors for resistance were compared into the two groups. Results: Among from 196 patients examined, 53 and 143 cases had early and late pneumonia, respectively. There was no significant difference between the early and late groups in regard to the frequency of MDR pathogens. There was no significant difference between the two groups with and without MDR in terms of age, gender, immune deficiency, duration of hospitalization and taking antibiotics. The most common early and late types were Acinetobacter baumannii (40.4%) and Klebsiella pneumoniae (31.8%), respectively and the minimal resistance of the bacteria was related to Colistin and amikacin antibiotics. Conclusion: Considering the high and increasing prevalence of antibiotic resistance, measures such as providing samples for culture before prescribing antibiotics, starting empirical treatment based on the frequency of agent pathogens and the rate of their antibiotic resistance and avoiding prescription without indication of antibiotics seem necessary.
Authors and Affiliations
Babak Alikiaii, Taghi Hashemi, Omid Aghadavoudi, Nasim Emami
Keywords
Related Articles
- EP ID EP311256
- DOI 10.9734/BJMMR/2017/30487
- Views 61
- Downloads 0
Possible Benefits of the Whole Body Vibration in the Treatment of Complications in Stroke Patients
Aims: A stroke is a neurological disorder and muscle weakness is the most prominent impairment. Whole-body vibration (WBV) is a possible modality of exercise that is useful for improving physical capacity, bone mass, bal...
Endarterectomy of the Totally & Subtotally Occluded Carotid Artery Facilitates the Surgery of the Stenosed Contralateral Side
Purpose: Patients with one side total/subtotal occlusion and contralateral side critical stenosis are high risk candidates for carotid interventions for the stenosed carotid side. We present our experiences with carotid...
Prevalence and Associated Risks Factors for Menstrual Disorders among Undergraduate Students in Borno State, Nigeria
Background: Problems pertaining to menstruation are generally perceived among women as normal variation in body physiology and often not regarded as a serious health issue that requires public health attention. They only...
Serum Vitamin D Concentration in Asthmatic Children and Its Association with Recovery Time from an Asthma Exacerbation
Introduction: The relationship of vitamin D and asthma is known but the association between vitamin D and time required to recover from acute asthma exacerbation has not been studied. Aims: To find an association betwee...
Risk Factors for First-line Antiretroviral Treatment Failure in HIV-1 Infected Children Attending Jos University Teaching Hospital, Jos, North Central Nigeria
Aim: To determine risk factors for first-line antiretroviral treatment failure in HIV-1 infected children attending Jos University Teaching Hospital, Jos. Study Design: Retrospective cohort study. Place and Duration of...