An Observational Study of Fetomaternal Outcome of Thyroid Disorder In Pregnancy In A Tertiary Care Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
Introduction: Thyroid disorder is most common in women’s as compare to male population. In females, this is the most common endocrine disorder during pregnancy resulting into abnormal maternal and fetal outcomes. Pregnancy is associated with profound changes in thyroid function. Many studies have reported that thyroid prevalence shows variation with age, sex, dietary habits, stress and geographical location. Materials and methods: This study is an observational study carried on 600 women coming for antenatal check-up in Tertiary Care Hospital in Jamshedpur from January 2017-December 2017. All women who were included in this study were followed from 20-24 weeks of pregnancy up to delivery. Results: It was observed that the maximum numbers of patients were in 20-25 years (51%) age group. Euthyroid (76%), hyperthyroid (02%), subclinical hyperthyroid (02%), hypothyroid (03%), and subclinical hypothyroid (08%) cases were detected. Neonatal jaundice developed in babies of all hyperthyroid patients, 50% of patients with Subclinical hyperthyroidism, 53% of patients with Hypothyroidism, 60% of patients with Subclinical Hypothyroidism and 11% of patients with Euthyroid. Conclusion: Gestational age specific reference intervals are of utmost importance by which clinicians can reliably evaluate thyroid function and monitor thyroxine replacement therapy in pregnant women. TPOAb (Thyroid peroxidase Antibody) positive patients are associated with an increased risk of abortion and these infants are more often born preterm. TSH is the hallmark in detection of hypothyroid as well hyperthyroid so TSH should be included in the list of routine investigations done in all antenatal women in first trimester. If TSH values are abnormal then FT3, FT4 and TPOAb need to be checked.
Authors and Affiliations
Dr. Manju Kumari Choudhary
Keywords
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- DOI 10.9790/0853-1708071719.
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