An Observational Study of Use of Azathioprine As Immonosuppresant For The Treatment Of Central Serous Retinopathy Associated With Tolosa Hunt Syndrome
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 1
Abstract
Tolosa Hunt syndrome is a rare disorder characterized by painful ophthalmoplegia by nonspecific inflammation of cavernous sinus or superior orbital fissure. In this disorder there is unilateral retroorbital pain and palsy of cranial nerve three, four, six and ophthalmic and maxillary subdivisions of trigeminal nerve. The disorder is often recurrent but usually responding well with glucocorticoid administration. The condition if present with central serous retinopathy is far rarer. Treatment of Tolosa Hunt syndrome with high dose steroid can precipitate central serous retinopathy but coexistence of the two condition is very much rare and if present together, there is therapeutic challenge where to use oral steroid or not. As steroid is contraindicated in this patient with good response. This result signifies azathioprine can be used as alternative therapy in conditions of Tolosa Hunt syndrome where steroid is contraindicated.
Authors and Affiliations
Raja Bhattacharya, Manab Nandy, Koushik Mukherjee, Purba Chakrabarty, Nirmal Polle
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