An Observational Study to Compare Effects of Dexmedetomidine with Levobupivacaine 0.5% and Levobupivacaine 0.5% alone for SCBP Block for Upper Limb Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2019, Vol 6, Issue 2
Abstract
Context: Dexmedetomidine, a potent α2 adrenoceptor agonist, is more selective towards the α2 adrenoceptor and have analgesic and sedative properties [3]. Levobupivacaine has been shown to be safe and effective for epidural/spinal anaesthesia and brachial plexus block [4]. Aims: To assess the safety, efficacy, onset & duration of sensory & motor block and rescue analgesia time of dexmedetomidine as an adjuvant to levobupivacaine 0.5% and levobupivacaine 0.5% alone in supraclavicular brachial plexus (SCBP) block. Material and methods: 60 patients aged 18-55 years of ASA I & II were divided randomly into two groups using chit method. Group LD (n=30) received 0.5% levobupivacaine 30 ml with inj. dexmedetomidine 1 μg kg-1 and Group L (n=30) 0.5% levobupivacaine 30 ml alone in SCBP block. Onset and duration of sensory & motor block, as well as duration of analgesia were assessed using pinprick, bromage score and visual analogue score respectively. Statistical analysis: The statistical analysis was assessed by unpaired t-test on Microsoft excel and IBM SPSS (Statistical Package for Social Sciences) version 21. P-value significant if <0.05. Results: The rescue analgesia time for Group LD was 1029.55 ± 95.87 and Group L was 657.93 ± 47.81 (p<0.0001). The onset of sensory & motor block was hastened, while duration was significantly prolonged in Group LD than Group L. Conclusion: Dexmedetomidine when added to levobupivacaine in SCBP block hastens the onset and prolongs duration of sensory & motor block and rescue analgesia time in the postoperative period with steady haemodynamics.
Authors and Affiliations
Karnavat Dhruval N
Keywords
Related Articles
- EP ID EP618863
- DOI 10.21088/ijaa.2349.8471.6219.8
- Views 85
- Downloads 0
Table Tilt Versus Pelvic Tilt Position for Preventing Hemodynamic Changes During Spinal Anaesthesia for Caesarean Section
Background: Hypotension is one of the most common complications associated with regional anaesthetic technique for CS. Several studies have been done for methods to prevent hypotension, which have been widely discussed i...
Haemodynamic Effects of LMA Fastrach versus Macintosh Laryngoscope While Intubation in Patients Undergoing Cabg
Coronary artery bypass grafting (CABG) surgery is still the predominant operative procedure for myocardial revascularization. The pressor response to intubation is a detrimental factor in these patients, where stable hem...
To Study the N-Acetylcysteine and Vitamin C Effect on Oxidative Stress in Abdominal Sepsis and Control Patients with Different Weight Range
"Sepsis" was characterized as the foundational reaction to infecdon, showed by at least 2 of the conditions recorded above for SIRS. "Serious sepsis" was characterized as sepsis related with organ dysflmction, hypoperfus...
Evaluation of Pre Incision Infiltration of A Local Anesthetics Regimen Prior to Modified Radical Mastectomy: A Randomized Single Blinded Study
Introduction: Breast surgery can be emotionally distressing and physically painful. Although regional anesthesia and nerve block techniques are widely used in many situations, many anesthetists are still minded by the si...
A Critical Evaluation of an Effect of Nalbuphine as an Adjuvant to Bupivacaine for Ultrasound Guided Interscalene Brachial Plexus Block
Context: The use of Brachial plexus block under Ultrasound guidance for Anesthesia has increased recently. Various adjuvants are added to enhance the analgesic effect of local anesthetic agents namely opioids, alpha 2 a...